Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.53 |
| ▸ | DAO | P14920 | 3/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | PGR | P06401 | 2/20 | 0.40 |
| ▸ | BRD4 | O60885 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.37 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.37 |
| ▸ | GRIA3 | P42263 | 1/20 | 0.37 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.37 |
| ▸ | MAOB | P27338 | 3/20 | 0.36 |
| ▸ | PARG | Q86W56 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.35 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.35 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.35 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24195933 | 1.00 | LMNA (0.53) | LMNADAOMAPTPGRBRD4 | |
| SCHEMBL24195937 | 0.93 | LMNA (0.53) | LMNADAOMAPTPGRBRD4 | |
| SCHEMBL21848325 | 0.83 | GRIA1 (0.57) | LMNADAOGRIA1GRIA2GRIA3 | |
| SCHEMBL31731190 | 0.81 | LMNA (0.54) | LMNADAOMAPTPGRBRD4 | |
| SCHEMBL27295360 | 0.79 | LMNA (0.53) | LMNADAOMAPTPGRBRD4 | |
| SCHEMBL16858454 | 0.76 | LMNA (0.49) | LMNADAOMAPTPGRBRD4 | |
| SCHEMBL30037778 | 0.76 | LMNA (0.49) | LMNAMAPTPGRBRD4MEN1 | |
| SCHEMBL31701670 | 0.74 | PGR (0.51) | PGR | |
| SCHEMBL25217626 | 0.73 | GRIN2D (0.56) | LMNAMAPTPGRBRD4MEN1 | |
| SCHEMBL13194494 | 0.73 | LMNA (0.50) | LMNADAOPGRBRD4MAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113924296-B | 1,3, 4-Oxadiazole derivative compounds as histone deacetylase 6 inhibitors and pharmaceutical compositions containing the same | 株式会社 钟根堂 | 2024-09-17 | — | — | CN | disclosed |