Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK9 | P50750 | 1/20 | 0.60 |
| ▸ | SALL4 | Q9UJQ4 | 2/20 | 0.50 |
| ▸ | BRD4 | O60885 | 1/20 | 0.47 |
| ▸ | TRIM24 | O15164 | 2/20 | 0.45 |
| ▸ | NR1H4 | Q96RI1 | 4/20 | 0.44 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.44 |
| ▸ | CDK2 | P24941 | 2/20 | 0.41 |
| ▸ | CLK1 | P49759 | 2/20 | 0.41 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.41 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.41 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | BRAF | P15056 | 1/20 | 0.40 |
| ▸ | LTA4H | P09960 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31193286 | 0.86 | CDK9 (0.55) | CDK9SALL4BRD4TRIM24NR1H4 | |
| SCHEMBL31193213 | 0.84 | CDK9 (0.84) | CDK9SALL4BRD4TRIM24NR1H4 | |
| SCHEMBL27075694 | 0.81 | CDK9 (0.61) | CDK9SALL4BRD4TRIM24NR1H4 | |
| SCHEMBL31193343 | 0.76 | BRD4 (0.44) | CDK9SALL4BRD4TRIM24TRIM33 | |
| SCHEMBL31193303 | 0.75 | BRD4 (0.59) | CDK9SALL4BRD4CDK2CLK4 | |
| SCHEMBL5880576 | 0.75 | CDK9 (0.90) | CDK9SALL4BRD4TRIM24NR1H4 | |
| SCHEMBL31193228 | 0.73 | TRIM33 (0.47) | CDK9SALL4BRD4TRIM33CLK4 | |
| SCHEMBL27104889 | 0.72 | CDK9 (0.79) | CDK9SALL4BRD4NR1H4TRIM33 | |
| SCHEMBL31193297 | 0.72 | GAA (0.53) | ALDH1A1BRAF | |
| SCHEMBL31193353 | 0.72 | BRAF (0.53) | CDK2ALDH1A1BRAF |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12129257-B1 | Imidazo[1,2-a]pyrazine compounds as CK2 inhibitors | King Faisal University (SA) | 2024-10-29 | — | — | US | claimed |
| US-12129257-B1 | Imidazo[1,2-a]pyrazine compounds as CK2 inhibitors | King Faisal University (SA) | 2024-10-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12129257-B1 | Imidazo[1,2-a]pyrazine compounds as CK2 inhibitors | CSNK2A1, CSNK2A2, CSNK1A1 | CDK9 126/4885SALL4 3184/4885BRD4 1059/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.