Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 2/20 | 0.44 |
| ▸ | CDK9 | P50750 | 1/20 | 0.43 |
| ▸ | PRKD3 | O94806 | 2/20 | 0.41 |
| ▸ | MAPK9 | P45984 | 2/20 | 0.41 |
| ▸ | CSNK1A1 | P48729 | 2/20 | 0.41 |
| ▸ | CSNK1D | P48730 | 2/20 | 0.41 |
| ▸ | GSK3B | P49841 | 2/20 | 0.41 |
| ▸ | PRKD2 | Q9BZL6 | 2/20 | 0.41 |
| ▸ | CLK4 | Q9HAZ1 | 2/20 | 0.41 |
| ▸ | CDK2 | P24941 | 1/20 | 0.41 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.41 |
| ▸ | SALL4 | Q9UJQ4 | 1/20 | 0.40 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.40 |
| ▸ | TRIM33 | Q9UPN9 | 3/20 | 0.39 |
| ▸ | ATM | Q13315 | 2/20 | 0.39 |
| ▸ | APAF1 | O14727 | 1/20 | 0.39 |
| ▸ | DYRK3 | O43781 | 1/20 | 0.39 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.39 |
| ▸ | FLT4 | P35916 | 1/20 | 0.39 |
| ▸ | KDR | P35968 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31193263 | 0.84 | CDK9 (0.60) | BRD4CDK9SALL4TRIM33ATM | |
| SCHEMBL31193225 | 0.82 | TRIM33 (0.47) | BRD4CDK9PRKD3MAPK9CSNK1A1 | |
| SCHEMBL31193228 | 0.82 | TRIM33 (0.47) | BRD4CDK9PRKD3MAPK9CSNK1A1 | |
| SCHEMBL31193303 | 0.76 | BRD4 (0.59) | BRD4CDK9PRKD3MAPK9CSNK1A1 | |
| SCHEMBL31193288 | 0.76 | CDK9 (0.60) | BRD4CDK9CLK4CDK2SALL4 | |
| SCHEMBL31193286 | 0.72 | CDK9 (0.55) | BRD4CDK9SALL4TRIM33GAA | |
| SCHEMBL31193313 | 0.72 | GAA (0.57) | SALL4GAAALDH1A1TP53MAPT | |
| SCHEMBL31193297 | 0.70 | GAA (0.53) | ATMGAAALDH1A1TP53MAPT | |
| SCHEMBL31193201 | 0.70 | MAPK13 (0.40) | BRD4CDK9PRKD3MAPK9CSNK1A1 | |
| SCHEMBL7980039 | 0.68 | BRD4 (0.67) | BRD4CDK9SALL4ATMAPAF1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12129257-B1 | Imidazo[1,2-a]pyrazine compounds as CK2 inhibitors | King Faisal University (SA) | 2024-10-29 | — | — | US | claimed |
| US-12129257-B1 | Imidazo[1,2-a]pyrazine compounds as CK2 inhibitors | King Faisal University (SA) | 2024-10-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12129257-B1 | Imidazo[1,2-a]pyrazine compounds as CK2 inhibitors | CSNK2A1, CSNK2A2, CSNK1A1 | BRD4 1059/4885CDK9 126/4885PRKD3 519/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.