SCHEMBL311973

SCHEMBL311973

CC(=O)Oc1ccc(C(=O)O)c(F)c1

nearest known ligand 0.67

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 6/20 0.67
MAPT P10636 1/20 0.51
MAPK1 P28482 1/20 0.51
ALDH1A1 P00352 5/20 0.49
PKM P14618 1/20 0.49
MAOB P27338 3/20 0.48
HSD17B10 Q99714 4/20 0.47
HPGD P15428 2/20 0.47
USP2 O75604 1/20 0.47
CYP2C19 P33261 1/20 0.47
CFD P00746 2/20 0.46
RARA P10276 1/20 0.46
RARB P10826 1/20 0.46
LMNA P02545 2/20 0.46
MAOA P21397 1/20 0.46
ELANE P08246 1/20 0.44
CYP3A4 P08684 1/20 0.44
ESR1 P03372 1/20 0.44
ITGB3 P05106 1/20 0.44
ITGA2B P08514 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26965229 0.86 KDM4E (0.62) KDM4EMAPTMAPK1ALDH1A1PKM
SCHEMBL312364 0.84 KDM4E (0.51) KDM4EMAPTMAPK1ALDH1A1PKM
SCHEMBL4360840 0.83 KDM4E (0.73) KDM4EMAPTMAPK1ALDH1A1PKM
SCHEMBL6692981 0.83 ALDH1A1 (0.49) KDM4EALDH1A1MAOBHSD17B10HPGD
SCHEMBL2590126 0.82 ALDH1A1 (0.71) KDM4EALDH1A1MAOBRARARARB
SCHEMBL1051747 0.81 CPS1 (0.63) KDM4EALDH1A1HPGDLMNA
SCHEMBL6446983 0.81 RARB (0.49) KDM4EALDH1A1MAOBRARARARB
SCHEMBL31621879 0.81 LMNA (0.52) KDM4EMAPTMAPK1PKMMAOB
SCHEMBL823757 0.81 LMNA (0.52) KDM4EMAPTMAPK1PKMMAOB
SCHEMBL25946840 0.80 ELANE (0.45) KDM4EMAPTALDH1A1MAOBHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 114 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119463143-A Polynaphthalate resin and preparation method thereof 四川大学 2025-02-18 CN claimed
JP-10279534-A None JP disclosed
JP-5085989-A None JP disclosed
JP-11080092-A None JP disclosed
JP-11310551-A None JP disclosed
JP-10087571-A None JP disclosed
JP-9165356-A None JP disclosed
JP-7316101-A None JP disclosed
CN-119463143-A Polynaphthalate resin and preparation method thereof 四川大学 2025-02-18 CN disclosed
US-8242130-B2 Flavanoids and isoflavanoids for the prevention and treatment of cardiovascular diseases RESVERLOGIX CORP. (CA) 2012-08-14 US disclosed
US-5248446-A Copolyethers from epoxy compounds, ferroelectricity IDEMITSU KOSAN CO., LTD. (JP) 1993-09-28 US disclosed
EP-0559088-A1 Dioxane type liquid crystal substance MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 1993-09-08 EP disclosed
US-5236619-A Benzothiazoles CANON KABUSHIKI KAISHA (JP) 1993-08-17 US disclosed
JP-H0585989-A FLUORINE-SUBSTITUTED LIQUID CRYSTAL SUBSTANCE MITSUBISHI GAS CHEM CO INC 1993-04-06 JP disclosed
US-5190686-A LIQUID-CRYSTALLINE COPOLYMER IDEMITSU KOSAN CO., LTD. (JP) 1993-03-02 US disclosed
EP-0517504-A1 Liquid crystal composition MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 1992-12-09 EP disclosed
EP-0497297-A2 Liquid crystal compound and liquid crystal display device MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 1992-08-05 EP disclosed
EP-0440061-A1 Mesomorphic compound, liquid crystal composition containing same, liquid crystal device using same and display apparatus CANON KABUSHIKI KAISHA (JP) 1991-08-07 EP disclosed
EP-0439170-A2 Mesomorphic compound, liquid crystal composition containing same, liquid crystal device using same and display apparatus CANON KABUSHIKI KAISHA (JP) 1991-07-31 EP disclosed
EP-0355772-A2 Liquid-crystalline copolymer IDEMITSU KOSAN COMPANY LIMITED (JP) 1990-02-28 EP disclosed