Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM4 | P08173 | 3/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.50 |
| ▸ | NPC1 | O15118 | 2/20 | 0.50 |
| ▸ | RAB9A | P51151 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | FAAH | O00519 | 2/20 | 0.48 |
| ▸ | GRIN2B | Q13224 | 8/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 4/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 4/20 | 0.46 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31198878 | 0.91 | MEN1 (0.52) | CHRM4MEN1KMT2ANPSR1SMN1; SMN2 | |
| SCHEMBL31198992 | 0.89 | SMN1; SMN2 (0.62) | CHRM4MEN1KMT2ANPSR1SMN1; SMN2 | |
| SCHEMBL25431193 | 0.86 | MEN1 (0.53) | CHRM4MEN1KMT2ANPSR1SMN1; SMN2 | |
| SCHEMBL31198723 | 0.81 | MEN1 (0.52) | CHRM4MEN1KMT2ANPSR1SMN1; SMN2 | |
| SCHEMBL31199071 | 0.81 | MEN1 (0.47) | CHRM4MEN1KMT2ANPSR1SMN1; SMN2 | |
| SCHEMBL31198857 | 0.80 | GPR119 (0.57) | SMN1; SMN2NPC1RAB9AMAPTCYP2C19 | |
| SCHEMBL31198952 | 0.80 | SMN1; SMN2 (0.52) | CHRM4MEN1KMT2ANPSR1SMN1; SMN2 | |
| SCHEMBL15140566 | 0.79 | SMN1; SMN2 (0.72) | CHRM4MEN1KMT2ANPSR1SMN1; SMN2 | |
| SCHEMBL4035554 | 0.79 | SMN1; SMN2 (0.72) | CHRM4MEN1KMT2ANPSR1SMN1; SMN2 | |
| SCHEMBL6749001 | 0.78 | SMN1; SMN2 (0.67) | CHRM4MEN1KMT2ANPSR1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4676922-A1 | BIFUNCTIONAL COMPOUNDS CAPABLE OF DEGRADING ANDROGEN RECEPTORS | Astrazeneca AB (SE) | 2026-01-14 | — | — | EP | disclosed |
| WO-2024189488-A1 | BIFUNCTIONAL COMPOUNDS CAPABLE OF DEGRADING ANDROGEN RECEPTORS | ASTRAZENECA AB (SE) | 2024-09-19 | — | — | WO | disclosed |