Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.52 |
| ▸ | NPC1 | O15118 | 2/20 | 0.52 |
| ▸ | RAB9A | P51151 | 2/20 | 0.52 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | FAAH | O00519 | 1/20 | 0.49 |
| ▸ | GRIN2B | Q13224 | 6/20 | 0.46 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | JAK2 | O60674 | 2/20 | 0.44 |
| ▸ | JAK1 | P23458 | 2/20 | 0.44 |
| ▸ | TYK2 | P29597 | 2/20 | 0.44 |
| ▸ | JAK3 | P52333 | 2/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.43 |
| ▸ | CCR1 | P32246 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31198832 | 0.94 | PDE4B (0.52) | SMN1; SMN2NPC1RAB9ACHRM4MEN1 | |
| SCHEMBL17477287 | 0.86 | SMN1; SMN2 (0.57) | SMN1; SMN2NPC1RAB9ACHRM4MEN1 | |
| SCHEMBL7503285 | 0.86 | SMN1; SMN2 (0.62) | SMN1; SMN2NPC1RAB9ACHRM4MEN1 | |
| SCHEMBL14922380 | 0.85 | SMN1; SMN2 (0.56) | SMN1; SMN2NPC1RAB9ACHRM4MEN1 | |
| SCHEMBL14922734 | 0.84 | SMN1; SMN2 (0.55) | SMN1; SMN2NPC1RAB9ACHRM4MEN1 | |
| SCHEMBL4035554 | 0.81 | SMN1; SMN2 (0.72) | SMN1; SMN2NPC1RAB9ACHRM4MEN1 | |
| SCHEMBL8316392 | 0.80 | SMN1; SMN2 (0.61) | SMN1; SMN2NPC1RAB9ACHRM4MEN1 | |
| SCHEMBL30711534 | 0.80 | CHRM4 (0.53) | SMN1; SMN2NPC1RAB9ACHRM4S1PR1 | |
| SCHEMBL31198766 | 0.80 | CHRM4 (0.53) | SMN1; SMN2NPC1RAB9ACHRM4MEN1 | |
| SCHEMBL6749001 | 0.80 | SMN1; SMN2 (0.67) | SMN1; SMN2NPC1RAB9ACHRM4MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4676922-A1 | BIFUNCTIONAL COMPOUNDS CAPABLE OF DEGRADING ANDROGEN RECEPTORS | Astrazeneca AB (SE) | 2026-01-14 | — | — | EP | disclosed |
| WO-2024189488-A1 | BIFUNCTIONAL COMPOUNDS CAPABLE OF DEGRADING ANDROGEN RECEPTORS | ASTRAZENECA AB (SE) | 2024-09-19 | — | — | WO | disclosed |