Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NTRK2 | Q16620 | 2/20 | 0.43 |
| ▸ | CLK4 | Q9HAZ1 | 2/20 | 0.43 |
| ▸ | DYRK1B | Q9Y463 | 2/20 | 0.43 |
| ▸ | TYRO3 | Q06418 | 1/20 | 0.43 |
| ▸ | GSK3B | P49841 | 2/20 | 0.39 |
| ▸ | JAK2 | O60674 | 1/20 | 0.39 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.39 |
| ▸ | MET | P08581 | 1/20 | 0.39 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.39 |
| ▸ | PRKACA | P17612 | 1/20 | 0.39 |
| ▸ | KDR | P35968 | 1/20 | 0.39 |
| ▸ | MAP2K2 | P36507 | 1/20 | 0.39 |
| ▸ | FLT3 | P36888 | 1/20 | 0.39 |
| ▸ | MAP2K1 | Q02750 | 1/20 | 0.39 |
| ▸ | MST1R | Q04912 | 1/20 | 0.39 |
| ▸ | NTRK3 | Q16288 | 1/20 | 0.39 |
| ▸ | CAMK1D | Q8IU85 | 1/20 | 0.39 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.37 |
| ▸ | FYN | P06241 | 1/20 | 0.36 |
| ▸ | CA12 | O43570 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31200245 | 1.00 | NTRK2 (0.43) | NTRK2CLK4DYRK1BTYRO3GSK3B | |
| SCHEMBL31200303 | 0.85 | GPR119 (0.41) | NTRK2CLK4DYRK1BTYRO3GSK3B | |
| SCHEMBL31200293 | 0.80 | PIK3CD (0.35) | TAS2R14PLGPLATLMNAVCP | |
| SCHEMBL31199988 | 0.74 | GRK2 (0.37) | GPR119LIPG | |
| SCHEMBL27085978 | 0.73 | NTRK2 (0.51) | NTRK2CLK4DYRK1BTYRO3GSK3B | |
| Oxalic Acid SCHEMBL2041964 | 0.72 | NTRK2 (0.49) | NTRK2CLK4DYRK1BTYRO3GSK3B | |
| SCHEMBL31037780 | 0.72 | NTRK2 (0.49) | NTRK2CLK4DYRK1BTYRO3GSK3B | |
| SCHEMBL15967764 | 0.71 | CLK4 (0.48) | NTRK2CLK4DYRK1BTYRO3GSK3B | |
| SCHEMBL28115873 | 0.70 | NTRK2 (0.49) | NTRK2CLK4DYRK1BTYRO3GSK3B | |
| SCHEMBL27085844 | 0.70 | HDAC6 (0.45) | NTRK2CLK4DYRK1BTYRO3GSK3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4709722-A1 | ISOXAZOLIDINES AS RIPK1 INHIBITORS AND USE THEREOF | GENZYME CORPORATION (US) | 2026-03-18 | — | — | EP | disclosed |
| WO-2024233547-A1 | ISOXAZOLIDINES AS RIPK1 INHIBITORS AND USE THEREOF | GENZYME CORPORATION (US) | 2024-11-14 | — | — | WO | disclosed |