Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CD | O00329 | 7/20 | 0.35 |
| ▸ | PIK3CB | P42338 | 7/20 | 0.35 |
| ▸ | PIK3CA | P42336 | 6/20 | 0.35 |
| ▸ | PIK3CG | P48736 | 4/20 | 0.35 |
| ▸ | TAS2R14 | Q9NYV8 | 3/20 | 0.34 |
| ▸ | VCP | P55072 | 2/20 | 0.34 |
| ▸ | PLG | P00747 | 1/20 | 0.34 |
| ▸ | PLAT | P00750 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.34 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.33 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.33 |
| ▸ | SELL | P14151 | 1/20 | 0.33 |
| ▸ | SELP | P16109 | 1/20 | 0.33 |
| ▸ | SELE | P16581 | 1/20 | 0.33 |
| ▸ | PIM1 | P11309 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31200346 | 0.87 | HPGD (0.36) | PIK3CDPIK3CBPIK3CAPIK3CG | |
| SCHEMBL31200245 | 0.80 | NTRK2 (0.43) | TAS2R14VCPPLGPLATLMNA | |
| SCHEMBL31200240 | 0.80 | NTRK2 (0.43) | TAS2R14VCPPLGPLATLMNA | |
| SCHEMBL15422809 | 0.79 | PLG (0.43) | TAS2R14VCPPLGPLATLMNA | |
| SCHEMBL31200145 | 0.76 | RIPK1 (0.35) | PIK3CDPIK3CBPIK3CAPIK3CGGRM2 | |
| SCHEMBL30349290 | 0.76 | GRM2 (0.35) | PIK3CDPIK3CBPIK3CAPIK3CGGRM2 | |
| SCHEMBL27085852 | 0.74 | GRM2 (0.44) | PIK3CDPIK3CBPIK3CAPIK3CGGRM2 | |
| SCHEMBL31200244 | 0.70 | PLG (0.40) | TAS2R14VCPPLGPLATLMNA | |
| SCHEMBL31200363 | 0.69 | TRPM8 (0.39) | TAS2R14VCPPLGPLATLMNA | |
| SCHEMBL31200225 | 0.68 | PLG (0.38) | TAS2R14VCPPLGPLATLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4709722-A1 | ISOXAZOLIDINES AS RIPK1 INHIBITORS AND USE THEREOF | GENZYME CORPORATION (US) | 2026-03-18 | — | — | EP | disclosed |
| WO-2024233547-A1 | ISOXAZOLIDINES AS RIPK1 INHIBITORS AND USE THEREOF | GENZYME CORPORATION (US) | 2024-11-14 | — | — | WO | disclosed |