SCHEMBL31200544

SCHEMBL31200544

O=C(O)N1CCC2OCCNC2C1

nearest known ligand 0.36

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
PADI4 Q9UM07 1/20 0.36
HRH4 Q9H3N8 2/20 0.32
MGLL Q99685 2/20 0.31
MBTD1 Q05BQ5 1/20 0.31
L3MBTL3 Q96JM7 1/20 0.31
CHRNB2 P17787 1/20 0.30
CHRNA3 P32297 1/20 0.30
CHRNA4 P43681 1/20 0.30
CHRNB3 Q05901 1/20 0.30
CHRNA6 Q15825 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18203968 0.87 HRH4 (0.32) HRH4MBTD1L3MBTL3
SCHEMBL18203969 0.87 HRH4 (0.32) HRH4MBTD1L3MBTL3
SCHEMBL15817410 0.87 HRH4 (0.32) HRH4MBTD1L3MBTL3
SCHEMBL4493153 0.85 HRH4 (0.33) HRH4
SCHEMBL18203900 0.85 HRH4 (0.33) HRH4
SCHEMBL16043980 0.85 HRH4 (0.33) HRH4
SCHEMBL26134382 0.85 HRH4 (0.33) HRH4
SCHEMBL30419630 0.85 HRH4 (0.33) HRH4
SCHEMBL23152274 0.83 MGLL (0.32) MGLL
SCHEMBL14964726 0.79 PDK1 (0.32)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4680601-A1 PYRIDAZINE COMPOUNDS, THEIR PREPARATION, AND THEIR THERAPEUTIC USES Sanofi (FR) 2026-01-21 EP disclosed
WO-2024188994-A1 PYRIDAZINE COMPOUNDS, THEIR PREPARATION, AND THEIR THERAPEUTIC USES SANOFI (FR) 2024-09-19 WO disclosed