Known targets — ChEMBL curated mechanism
ACHEADRA2AADRA2BADRA2CBCHECHRNA4CHRNB2GHSRMAOBUGCG
The experimentally established mechanism targets of Tartaric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNB2 known ✓ | P17787 | 1/20 | 0.32 |
| ▸ | CHRNA4 known ✓ | P43681 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | GBA1 | P04062 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 2/20 | 0.34 |
| ▸ | CA12 | O43570 | 1/20 | 0.34 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
| ▸ | CA9 | Q16790 | 1/20 | 0.34 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.34 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.34 |
| ▸ | CHKA | P35790 | 1/20 | 0.33 |
| ▸ | PHGDH | O43175 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.32 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.32 |
| ▸ | CHRNB3 | Q05901 | 1/20 | 0.32 |
| ▸ | CHRNA6 | Q15825 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Cadaverine Tartrate SCHEMBL30171032 | 0.98 | TSHR (0.43) | TSHRNFKB1CYP2C19GBA1CA2 | |
| Methylpiperazine SCHEMBL27990335 | 0.85 | TP53 (0.48) | CYP2C19CA2CA12CA1CA9 | |
| Methylpiperazine SCHEMBL16669183 | 0.82 | CA2 (0.42) | TSHRCA2CA12CA1CA9 | |
| Methylpiperazine SCHEMBL1681596 | 0.80 | CYP1A2 (0.44) | CA2CA12CA1CA9CHRM5 | |
| Methylpiperazine SCHEMBL7487241 | 0.80 | CA2 (0.41) | CA2CA12CA1CA9CHKA | |
| Cadaverine Tartrate SCHEMBL8734652 | 0.79 | TSHR (0.67) | TSHRNFKB1CYP2C19GBA1TDP1 | |
| Methylpiperazine SCHEMBL27962682 | 0.79 | TP53 (0.41) | CA2CA12CA1CA9CHRM5 | |
| Cadaverine Tartrate SCHEMBL1574315 | 0.78 | TSHR (0.52) | TSHRNFKB1CYP2C19KMT2ASIGMAR1 | |
| Methylpiperazine SCHEMBL9400626 | 0.78 | CA2 (0.39) | CA2CA12CA1CA9CHRM5 | |
| Methylpiperazine SCHEMBL8607131 | 0.78 | CA2 (0.39) | CA2CA12CA1CA9CHRM5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118580223-A | Xinafoate salts of JAK inhibiting compounds | 阿斯利康(瑞典)有限公司 | 2024-09-03 | — | — | CN | claimed |