Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | JAK2 | O60674 | 2/20 | 0.62 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.62 |
| ▸ | CTSC | P53634 | 3/20 | 0.54 |
| ▸ | STK17A | Q9UEE5 | 8/20 | 0.52 |
| ▸ | AURKA | O14965 | 3/20 | 0.52 |
| ▸ | ALK | Q9UM73 | 3/20 | 0.52 |
| ▸ | CDK19 | Q9BWU1 | 1/20 | 0.52 |
| ▸ | STK17B | O94768 | 6/20 | 0.52 |
| ▸ | CDK2 | P24941 | 2/20 | 0.51 |
| ▸ | NTRK1 | P04629 | 2/20 | 0.51 |
| ▸ | IGF1R | P08069 | 2/20 | 0.51 |
| ▸ | PLK4 | O00444 | 1/20 | 0.51 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.51 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.51 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.51 |
| ▸ | INSR | P06213 | 1/20 | 0.51 |
| ▸ | LCK | P06239 | 1/20 | 0.51 |
| ▸ | FYN | P06241 | 1/20 | 0.51 |
| ▸ | CDK1 | P06493 | 1/20 | 0.51 |
| ▸ | FES | P07332 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1936618 | 0.82 | NTRK1 (0.47) | JAK2LRRK2CTSCSTK17ASTK17B | |
| SCHEMBL3120620 | 0.81 | JAK2 (0.62) | JAK2LRRK2CTSCSTK17AAURKA | |
| SCHEMBL29816634 | 0.81 | JAK2 (0.79) | JAK2LRRK2CTSCSTK17AAURKA | |
| SCHEMBL15391316 | 0.81 | JAK2 (0.79) | JAK2LRRK2CTSCSTK17AAURKA | |
| SCHEMBL29695586 | 0.80 | JAK2 (0.68) | JAK2LRRK2CTSCSTK17AALK | |
| SCHEMBL24842785 | 0.76 | CTSC (0.71) | JAK2LRRK2CTSCSTK17AAURKA | |
| SCHEMBL29816755 | 0.76 | CTSC (0.71) | JAK2LRRK2CTSCSTK17AAURKA | |
| SCHEMBL29816852 | 0.76 | CTSC (0.71) | JAK2LRRK2CTSCSTK17AAURKA | |
| SCHEMBL24842761 | 0.76 | CTSC (0.71) | JAK2LRRK2CTSCSTK17AAURKA | |
| SCHEMBL1935123 | 0.75 | ALDH1A1 (0.41) | STK17ASTK17BMAP4K4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010025871-A1 | 4-HALOGEN ALKYL-SUBSTITUTED DIAMINOPYRIMIDINES FOR USE AS FUNGICIDES | BAYER CROPSCIENCE AG (DE) | 2010-03-11 | — | — | WO | disclosed |
| EP-2161259-A1 | 4-Haloalkyl substituted Diaminopyrimidine | Bayer CropScience AG (DE) | 2010-03-10 | — | — | EP | disclosed |