Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CACNA2D1 | P54289 | 1/20 | 0.41 |
| ▸ | CDK7 | P50613 | 2/20 | 0.38 |
| ▸ | HTR7 | P34969 | 6/20 | 0.37 |
| ▸ | PIM1 | P11309 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | BRD4 | O60885 | 2/20 | 0.34 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.34 |
| ▸ | CDK2 | P24941 | 1/20 | 0.34 |
| ▸ | CDK9 | P50750 | 1/20 | 0.34 |
| ▸ | CCNH | P51946 | 1/20 | 0.34 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.34 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | TNKS | O95271 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31201218 | 0.94 | CCNK (0.39) | CACNA2D1CDK7HTR7SMN1; SMN2RECQL | |
| SCHEMBL31201418 | 0.91 | GSK3B (0.35) | CACNA2D1CDK7CDK2CDK9TNKS | |
| SCHEMBL31201302 | 0.90 | CDK2 (0.37) | CACNA2D1CDK7PIM1CCNT1CDK2 | |
| SCHEMBL31201492 | 0.89 | CDK7 (0.45) | CACNA2D1CDK7SMN1; SMN2BRD4CCNT1 | |
| SCHEMBL31201336 | 0.86 | GABRA1 (0.45) | CACNA2D1LMNANPC1RAB9A | |
| SCHEMBL31201363 | 0.85 | GSK3B (0.39) | CACNA2D1CDK7 | |
| SCHEMBL31201280 | 0.84 | CACNA2D1 (0.45) | CACNA2D1CDK7HTR7PIM1SMN1; SMN2 | |
| SCHEMBL31201375 | 0.84 | CDK7 (0.53) | CDK7SMN1; SMN2CCNT1CDK2CDK9 | |
| SCHEMBL31201350 | 0.83 | GABRA1 (0.33) | CDK7BRD4CCNT1CDK2CDK9 | |
| SCHEMBL31201150 | 0.83 | TYK2 (0.36) | CACNA2D1CDK7RECQLBRD4CCNT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4727944-A1 | [1,2,4]-TRIAZOLO[4,3-B]PYRIDAZINE DERIVATIVES USEFUL AS A MEDICAMENT | Perha Pharmaceuticals (FR) | 2026-04-22 | — | — | EP | claimed |
| WO-2024256496-A1 | [1,2,4]-TRIAZOLO[4,3-B]PYRIDAZINE DERIVATIVES USEFUL AS A MEDICAMENT | PERHA PHARMACEUTICALS (FR) | 2024-12-19 | — | — | WO | claimed |
| EP-4477653-A1 | [1,2,4]-TRIAZOLO[4,3-B]PYRIDAZINE DERIVATIVES USEFUL AS A MEDICAMENT | Perha Pharmaceuticals (FR) | 2024-12-18 | — | — | EP | claimed |
| EP-4727944-A1 | [1,2,4]-TRIAZOLO[4,3-B]PYRIDAZINE DERIVATIVES USEFUL AS A MEDICAMENT | Perha Pharmaceuticals (FR) | 2026-04-22 | — | — | EP | disclosed |
| WO-2024256496-A1 | [1,2,4]-TRIAZOLO[4,3-B]PYRIDAZINE DERIVATIVES USEFUL AS A MEDICAMENT | PERHA PHARMACEUTICALS (FR) | 2024-12-19 | — | — | WO | disclosed |
| EP-4477653-A1 | [1,2,4]-TRIAZOLO[4,3-B]PYRIDAZINE DERIVATIVES USEFUL AS A MEDICAMENT | Perha Pharmaceuticals (FR) | 2024-12-18 | — | — | EP | disclosed |