Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3B | P49841 | 5/20 | 0.35 |
| ▸ | CACNA2D1 | P54289 | 1/20 | 0.33 |
| ▸ | GSK3A | P49840 | 4/20 | 0.32 |
| ▸ | TNKS | O95271 | 1/20 | 0.32 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.32 |
| ▸ | ACP1 | P24666 | 1/20 | 0.32 |
| ▸ | PGK1 | P00558 | 1/20 | 0.32 |
| ▸ | CDK7 | P50613 | 1/20 | 0.32 |
| ▸ | FYN | P06241 | 4/20 | 0.31 |
| ▸ | CDK2 | P24941 | 2/20 | 0.30 |
| ▸ | CDK9 | P50750 | 1/20 | 0.30 |
| ▸ | TRPC5 | Q9UL62 | 1/20 | 0.30 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.30 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.30 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.30 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.30 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.30 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31201363 | 0.94 | GSK3B (0.39) | GSK3BCACNA2D1GSK3AACP1CDK7 | |
| SCHEMBL31201176 | 0.91 | CACNA2D1 (0.41) | CACNA2D1TNKSTNKS2CDK7CDK2 | |
| SCHEMBL31201345 | 0.90 | CDK7 (0.38) | CDK7FYNCDK2CDK9 | |
| SCHEMBL31201302 | 0.89 | CDK2 (0.37) | GSK3BCACNA2D1GSK3ACDK7CDK2 | |
| SCHEMBL31201218 | 0.85 | CCNK (0.39) | CACNA2D1CDK7CDK2CDK9 | |
| SCHEMBL31201327 | 0.84 | FLT3 (0.35) | GSK3BCACNA2D1GSK3ATNKSTNKS2 | |
| SCHEMBL31201299 | 0.84 | GSK3B (0.43) | GSK3BGSK3AACP1CDK7CDK2 | |
| SCHEMBL31201421 | 0.83 | CDK2 (0.34) | FYNCDK2CDK9GABRA1GABRG2 | |
| SCHEMBL31201350 | 0.82 | GABRA1 (0.33) | CDK7FYNCDK2CDK9GABRA1 | |
| SCHEMBL31201508 | 0.82 | GSK3B (0.43) | GSK3BCACNA2D1GSK3ATNKSTNKS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4727944-A1 | [1,2,4]-TRIAZOLO[4,3-B]PYRIDAZINE DERIVATIVES USEFUL AS A MEDICAMENT | Perha Pharmaceuticals (FR) | 2026-04-22 | — | — | EP | claimed |
| WO-2024256496-A1 | [1,2,4]-TRIAZOLO[4,3-B]PYRIDAZINE DERIVATIVES USEFUL AS A MEDICAMENT | PERHA PHARMACEUTICALS (FR) | 2024-12-19 | — | — | WO | claimed |
| EP-4477653-A1 | [1,2,4]-TRIAZOLO[4,3-B]PYRIDAZINE DERIVATIVES USEFUL AS A MEDICAMENT | Perha Pharmaceuticals (FR) | 2024-12-18 | — | — | EP | claimed |
| EP-4727944-A1 | [1,2,4]-TRIAZOLO[4,3-B]PYRIDAZINE DERIVATIVES USEFUL AS A MEDICAMENT | Perha Pharmaceuticals (FR) | 2026-04-22 | — | — | EP | disclosed |
| WO-2024256496-A1 | [1,2,4]-TRIAZOLO[4,3-B]PYRIDAZINE DERIVATIVES USEFUL AS A MEDICAMENT | PERHA PHARMACEUTICALS (FR) | 2024-12-19 | — | — | WO | disclosed |
| EP-4477653-A1 | [1,2,4]-TRIAZOLO[4,3-B]PYRIDAZINE DERIVATIVES USEFUL AS A MEDICAMENT | Perha Pharmaceuticals (FR) | 2024-12-18 | — | — | EP | disclosed |