Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRG2 | P18507 | 8/20 | 0.44 |
| ▸ | GABRB3 | P28472 | 8/20 | 0.44 |
| ▸ | GABRA5 | P31644 | 8/20 | 0.44 |
| ▸ | GABRA3 | P34903 | 8/20 | 0.44 |
| ▸ | GABRA2 | P47869 | 8/20 | 0.44 |
| ▸ | GABRA1 | P14867 | 7/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | MKNK1 | Q9BUB5 | 2/20 | 0.37 |
| ▸ | OGA | O60502 | 1/20 | 0.36 |
| ▸ | CACNA2D1 | P54289 | 1/20 | 0.35 |
| ▸ | IGF1R | P08069 | 1/20 | 0.35 |
| ▸ | APP | P05067 | 2/20 | 0.34 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | GSK3A | P49840 | 1/20 | 0.34 |
| ▸ | GSK3B | P49841 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31201289 | 0.95 | GABRA1 (0.42) | GABRG2GABRB3GABRA5GABRA3GABRA2 | |
| SCHEMBL31201343 | 0.91 | GABRG2 (0.46) | GABRG2GABRB3GABRA5GABRA3GABRA2 | |
| SCHEMBL31201188 | 0.87 | GABRA1 (0.45) | GABRG2GABRB3GABRA5GABRA3GABRA2 | |
| SCHEMBL31201209 | 0.87 | GABRA1 (0.47) | GABRG2GABRB3GABRA5GABRA3GABRA2 | |
| SCHEMBL31201070 | 0.87 | CACNA2D1 (0.41) | GABRG2GABRB3GABRA5GABRA3GABRA2 | |
| SCHEMBL31201529 | 0.86 | GABRA1 (0.44) | GABRG2GABRB3GABRA5GABRA3GABRA2 | |
| SCHEMBL31201279 | 0.86 | CDK2 (0.43) | GABRG2GABRB3GABRA5GABRA3GABRA2 | |
| SCHEMBL31201241 | 0.86 | CDK2 (0.43) | GABRG2GABRB3GABRA5GABRA3GABRA2 | |
| SCHEMBL31201327 | 0.85 | FLT3 (0.35) | GABRG2GABRB3GABRA5GABRA3GABRA2 | |
| SCHEMBL31201336 | 0.84 | GABRA1 (0.45) | GABRG2GABRB3GABRA5GABRA3GABRA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4727944-A1 | [1,2,4]-TRIAZOLO[4,3-B]PYRIDAZINE DERIVATIVES USEFUL AS A MEDICAMENT | Perha Pharmaceuticals (FR) | 2026-04-22 | — | — | EP | claimed |
| WO-2024256496-A1 | [1,2,4]-TRIAZOLO[4,3-B]PYRIDAZINE DERIVATIVES USEFUL AS A MEDICAMENT | PERHA PHARMACEUTICALS (FR) | 2024-12-19 | — | — | WO | claimed |
| EP-4477653-A1 | [1,2,4]-TRIAZOLO[4,3-B]PYRIDAZINE DERIVATIVES USEFUL AS A MEDICAMENT | Perha Pharmaceuticals (FR) | 2024-12-18 | — | — | EP | claimed |
| EP-4727944-A1 | [1,2,4]-TRIAZOLO[4,3-B]PYRIDAZINE DERIVATIVES USEFUL AS A MEDICAMENT | Perha Pharmaceuticals (FR) | 2026-04-22 | — | — | EP | disclosed |
| WO-2024256496-A1 | [1,2,4]-TRIAZOLO[4,3-B]PYRIDAZINE DERIVATIVES USEFUL AS A MEDICAMENT | PERHA PHARMACEUTICALS (FR) | 2024-12-19 | — | — | WO | disclosed |
| EP-4477653-A1 | [1,2,4]-TRIAZOLO[4,3-B]PYRIDAZINE DERIVATIVES USEFUL AS A MEDICAMENT | Perha Pharmaceuticals (FR) | 2024-12-18 | — | — | EP | disclosed |