Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 6/20 | 0.49 |
| ▸ | HDAC6 | Q9UBN7 | 6/20 | 0.49 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.43 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.43 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | MITF | O75030 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31201590 | 0.81 | SMN1; SMN2 (0.45) | HDAC1HDAC6MAPTLMNACYP11B1 | |
| SCHEMBL25416318 | 0.81 | CYP19A1 (0.48) | HDAC1HDAC6MAPTLMNACYP11B1 | |
| SCHEMBL28857469 | 0.80 | HDAC1 (0.48) | HDAC1HDAC6MAPTLMNACYP11B1 | |
| SCHEMBL2276464 | 0.80 | LMNA (0.50) | HDAC1HDAC6MAPTLMNACYP11B1 | |
| SCHEMBL31201753 | 0.79 | CYP11B1 (0.44) | HDAC1HDAC6MAPTCYP11B1CYP11B2 | |
| SCHEMBL30992851 | 0.77 | ALDH1A1 (0.46) | HDAC1HDAC6MAPTLMNACYP11B1 | |
| SCHEMBL31272149 | 0.77 | POLB (0.40) | HDAC1HDAC6MAPTLMNAKMT2A | |
| SCHEMBL31201452 | 0.76 | LMNA (0.43) | HDAC1HDAC6MAPTLMNAKMT2A | |
| SCHEMBL2578582 | 0.75 | HDAC1 (0.64) | HDAC1HDAC6MAPTLMNACYP11B1 | |
| SCHEMBL18366892 | 0.75 | HDAC1 (0.53) | HDAC1HDAC6LMNARAB9ANPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4709725-A1 | HETEROCYCLIC COMPOUNDS AND USES THEREOF | Progentos Therapeutics, Inc. (US) | 2026-03-18 | — | — | EP | disclosed |
| WO-2024233642-A1 | HETEROCYCLIC COMPOUNDS AND USES THEREOF | PROGENTOS THERAPEUTICS, INC. (US) | 2024-11-14 | — | — | WO | disclosed |