Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXFP1 | Q9HBX9 | 5/20 | 0.55 |
| ▸ | GAA | P10253 | 5/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.50 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 2/20 | 0.49 |
| ▸ | RAB9A | P51151 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | RPS6KA3 | P51812 | 1/20 | 0.46 |
| ▸ | CRHBP | P24387 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29168823 | 0.85 | PTGS1 (0.68) | RXFP1PTGS1SMN1; SMN2NPC1RAB9A | |
| SCHEMBL21261424 | 0.80 | GAA (0.71) | GAAALDH1A1CYP1A2CYP3A4ALOX12 | |
| SCHEMBL11137549 | 0.80 | EPHX2 (0.57) | RXFP1MAPTPTGS1SMN1; SMN2NPC1 | |
| SCHEMBL11041709 | 0.78 | KMT2A (0.66) | GAAALDH1A1CYP1A2CYP3A4ALOX12 | |
| SCHEMBL30602809 | 0.75 | IDO1 (0.46) | GAAALDH1A1ALOX12MAPTSMN1; SMN2 | |
| SCHEMBL20984340 | 0.73 | EPHX2 (0.59) | PTGS1NPC1RAB9ATRPV1EPHX2 | |
| SCHEMBL6879918 | 0.73 | MEN1 (0.50) | RXFP1GAAALDH1A1SMN1; SMN2NPC1 | |
| SCHEMBL31078465 | 0.72 | RORC (0.71) | RXFP1MAPTPTGS1SMN1; SMN2NPC1 | |
| SCHEMBL28871750 | 0.72 | TLR7 (0.74) | SMN1; SMN2NPC1RAB9ATRPV1 | |
| SCHEMBL15529405 | 0.72 | RXFP1 (0.90) | RXFP1MAPTPTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119095828-A | Indazole compound, preparation method and application thereof in medicine | 江苏恒瑞医药股份有限公司 | 2024-12-06 | — | — | CN | disclosed |