Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 6/20 | 0.44 |
| ▸ | LMNA | P02545 | 4/20 | 0.44 |
| ▸ | TP53 | P04637 | 2/20 | 0.44 |
| ▸ | TNNI3K | Q59H18 | 1/20 | 0.43 |
| ▸ | TEAD1 | P28347 | 2/20 | 0.41 |
| ▸ | YAP1 | P46937 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 3/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31202807 | 0.75 | RXFP1 (0.55) | MAPTMEN1KMT2AGAATRPV1 | |
| SCHEMBL20767220 | 0.73 | TEAD1 (0.49) | IDO1MAPTLMNATP53TNNI3K | |
| SCHEMBL20766300 | 0.73 | TEAD1 (0.53) | IDO1MAPTLMNATP53TNNI3K | |
| SCHEMBL30602792 | 0.72 | LMNA (0.45) | LMNAMEN1KMT2AMAPK1GAA | |
| SCHEMBL20766837 | 0.71 | TEAD1 (0.54) | IDO1MAPTLMNATP53TNNI3K | |
| SCHEMBL4002880 | 0.71 | MAPT (0.68) | IDO1MAPTLMNATP53MEN1 | |
| SCHEMBL2371994 | 0.71 | ALDH1A1 (0.68) | IDO1MAPTLMNATNNI3KGAA | |
| SCHEMBL22635666 | 0.70 | ALDH1A1 (0.58) | IDO1MAPTTNNI3KTEAD1YAP1 | |
| SCHEMBL22635632 | 0.68 | TEAD1 (0.48) | IDO1MAPTLMNATP53TNNI3K | |
| SCHEMBL4000903 | 0.68 | MEN1 (0.63) | MAPTLMNATP53TNNI3KMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119095828-A | Indazole compound, preparation method and application thereof in medicine | 江苏恒瑞医药股份有限公司 | 2024-12-06 | — | — | CN | disclosed |
| WO-2023186058-A1 | INDAZOLE COMPOUND, PREPARATION METHOD THEREFOR, AND USE THEREOF IN MEDICINE | 江苏恒瑞医药股份有限公司 | 2023-10-05 | — | — | WO | disclosed |