Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | VRK1 | Q99986 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.31 |
| ▸ | USP7 | Q93009 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31185905 | 0.78 | SCN9A (0.31) | — | |
| SCHEMBL12563479 | 0.75 | TAAR1 (0.42) | USP7 | |
| SCHEMBL24696640 | 0.72 | MAP4K4 (0.34) | VRK1CPB2 | |
| SCHEMBL18125543 | 0.72 | CYP11B1 (0.42) | KMT2AUSP7 | |
| SCHEMBL16610671 | 0.71 | HDAC1 (0.39) | — | |
| SCHEMBL25346943 | 0.71 | PDGFRB (0.40) | VRK1HTTKMT2ACPB2USP7 | |
| SCHEMBL30723523 | 0.70 | APP (0.38) | — | |
| SCHEMBL23641450 | 0.70 | APP (0.38) | — | |
| SCHEMBL30508280 | 0.70 | TSHR (0.41) | KMT2A | |
| SCHEMBL31181376 | 0.69 | ALDH1A1 (0.45) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118974033-A | Bcl-xL inhibitors | 百济神州有限公司 | 2024-11-15 | — | — | CN | disclosed |