Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CG | P48736 | 8/20 | 0.52 |
| ▸ | GSK3B | P49841 | 1/20 | 0.41 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.41 |
| ▸ | PIK3CA | P42336 | 5/20 | 0.39 |
| ▸ | ROCK2 | O75116 | 3/20 | 0.39 |
| ▸ | TTK | P33981 | 3/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | PIK3CD | O00329 | 2/20 | 0.38 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.38 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.38 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.38 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31204096 | 0.76 | PIK3CG (0.51) | PIK3CGGSK3BDYRK1APIK3CAROCK2 | |
| SCHEMBL936127 | 0.75 | PIK3CG (0.63) | PIK3CGPIK3CAPIK3CDPIK3CB | |
| SCHEMBL968074 | 0.73 | AHR (0.46) | PIK3CGPIK3CATTKPIK3CDPIK3CB | |
| SCHEMBL31204112 | 0.69 | PIK3CG (0.41) | PIK3CGPIK3CAPIK3CDPIK3CB | |
| SCHEMBL31286957 | 0.69 | HDAC8 (0.41) | PIK3CGPIK3CATTKRAB9APIK3CD | |
| SCHEMBL2771935 | 0.69 | TTK (0.62) | PIK3CGTTKNPC1RAB9AADORA1 | |
| SCHEMBL16439342 | 0.68 | AHR (0.53) | PIK3CGPIK3CAPIK3CDPIK3CB | |
| SCHEMBL15219428 | 0.68 | MET (0.46) | GSK3BDYRK1AALDH1A1HTTSMN1; SMN2 | |
| SCHEMBL2788075 | 0.67 | PIK3CA (0.54) | PIK3CGPIK3CAROCK2TTKNPC1 | |
| SCHEMBL31176823 | 0.66 | CYP1A2 (0.46) | GSK3BDYRK1AALDH1A1HTTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4727938-A1 | BICYCLIC HETEROAROMATIC COMPOUNDS FOR TREATING NEUROLOGICAL DISORDERS | Prothena Biosciences Limited (IE) | 2026-04-22 | — | — | EP | disclosed |
| WO-2024259121-A1 | BICYCLIC HETEROAROMATIC COMPOUNDS FOR TREATING NEUROLOGICAL DISORDERS | PROTHENA BIOSCIENCES LIMITED (IE) | 2024-12-19 | — | — | WO | disclosed |