Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CG | P48736 | 10/20 | 0.41 |
| ▸ | PIK3CA | P42336 | 7/20 | 0.41 |
| ▸ | AHR | P35869 | 7/20 | 0.40 |
| ▸ | PIK3CD | O00329 | 4/20 | 0.39 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.39 |
| ▸ | JAK2 | O60674 | 1/20 | 0.38 |
| ▸ | JAK1 | P23458 | 1/20 | 0.38 |
| ▸ | TYK2 | P29597 | 1/20 | 0.38 |
| ▸ | JAK3 | P52333 | 1/20 | 0.38 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL968074 | 0.78 | AHR (0.46) | PIK3CGPIK3CAAHRPIK3CDPIK3CB | |
| SCHEMBL936127 | 0.78 | PIK3CG (0.63) | PIK3CGPIK3CAAHRPIK3CDPIK3CB | |
| SCHEMBL31204146 | 0.78 | JAK2 (0.39) | PIK3CGJAK2JAK1TYK2JAK3 | |
| SCHEMBL31204259 | 0.75 | MAP3K5 (0.53) | PIK3CGPIK3CA | |
| SCHEMBL31204203 | 0.74 | OTUD7B (0.47) | PIK3CGPIK3CAPIK3CDPIK3CB | |
| SCHEMBL2771935 | 0.74 | TTK (0.62) | PIK3CGAHR | |
| SCHEMBL31204072 | 0.71 | JAK2 (0.34) | JAK2JAK1TYK2JAK3 | |
| SCHEMBL16439342 | 0.70 | AHR (0.53) | PIK3CGPIK3CAAHRPIK3CDPIK3CB | |
| SCHEMBL31204279 | 0.69 | PIK3CG (0.52) | PIK3CGPIK3CAPIK3CDPIK3CB | |
| SCHEMBL2788075 | 0.69 | PIK3CA (0.54) | PIK3CGPIK3CA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4727938-A1 | BICYCLIC HETEROAROMATIC COMPOUNDS FOR TREATING NEUROLOGICAL DISORDERS | Prothena Biosciences Limited (IE) | 2026-04-22 | — | — | EP | disclosed |
| WO-2024259121-A1 | BICYCLIC HETEROAROMATIC COMPOUNDS FOR TREATING NEUROLOGICAL DISORDERS | PROTHENA BIOSCIENCES LIMITED (IE) | 2024-12-19 | — | — | WO | disclosed |