Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 7/20 | 0.72 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.72 |
| ▸ | MAPT | P10636 | 4/20 | 0.72 |
| ▸ | LMNA | P02545 | 2/20 | 0.72 |
| ▸ | HTT | P42858 | 2/20 | 0.72 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.72 |
| ▸ | RAB9A | P51151 | 5/20 | 0.71 |
| ▸ | NPC1 | O15118 | 4/20 | 0.71 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.69 |
| ▸ | GAA | P10253 | 2/20 | 0.68 |
| ▸ | POLB | P06746 | 1/20 | 0.68 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.66 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.66 |
| ▸ | CA12 | O43570 | 2/20 | 0.65 |
| ▸ | CA1 | P00915 | 2/20 | 0.65 |
| ▸ | CA2 | P00918 | 2/20 | 0.65 |
| ▸ | CA9 | Q16790 | 2/20 | 0.65 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.63 |
| ▸ | FADS1 | O60427 | 1/20 | 0.61 |
| ▸ | GRIK1 | P39086 | 2/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1877777 | 1.00 | MEN1 (0.72) | MEN1KMT2AMAPTLMNAHTT | |
| SCHEMBL4301183 | 0.90 | KMT2A (0.82) | MEN1KMT2AMAPTLMNAHTT | |
| SCHEMBL6227431 | 0.86 | MEN1 (0.74) | MEN1KMT2AMAPTLMNAHTT | |
| SCHEMBL2682054 | 0.85 | KMT2A (1.00) | MEN1KMT2AMAPTLMNAHTT | |
| SCHEMBL29533340 | 0.83 | MEN1 (1.00) | MEN1KMT2AMAPTLMNAHTT | |
| SCHEMBL10344695 | 0.83 | MEN1 (1.00) | MEN1KMT2AMAPTLMNAHTT | |
| SCHEMBL13666033 | 0.83 | MEN1 (0.70) | MEN1KMT2AMAPTLMNAHTT | |
| SCHEMBL17079616 | 0.83 | DDX3X (0.79) | MEN1KMT2AMAPTLMNAHTT | |
| SCHEMBL6227015 | 0.83 | MEN1 (0.71) | MEN1KMT2AMAPTLMNAHTT | |
| SCHEMBL6436269 | 0.82 | MEN1 (0.72) | MEN1KMT2AMAPTLMNAHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113271941-B | Urea derivatives for the treatment and/or prophylaxis of cancer | 法国国家科学研究中心 | 2024-09-20 | — | — | CN | disclosed |