Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 10/20 | 0.82 |
| ▸ | MEN1 | O00255 | 9/20 | 0.82 |
| ▸ | MAPT | P10636 | 6/20 | 0.82 |
| ▸ | LMNA | P02545 | 4/20 | 0.82 |
| ▸ | HTT | P42858 | 4/20 | 0.82 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.82 |
| ▸ | RAB9A | P51151 | 5/20 | 0.80 |
| ▸ | NPC1 | O15118 | 4/20 | 0.80 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.77 |
| ▸ | GAA | P10253 | 1/20 | 0.73 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.73 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.73 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.68 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.65 |
| ▸ | PPIA | P62937 | 1/20 | 0.64 |
| ▸ | RECQL | P46063 | 1/20 | 0.64 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.62 |
| ▸ | KDR | P35968 | 1/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6227431 | 0.92 | MEN1 (0.74) | KMT2AMEN1MAPTLMNAHTT | |
| SCHEMBL2682054 | 0.91 | KMT2A (1.00) | KMT2AMEN1MAPTLMNAHTT | |
| SCHEMBL1877777 | 0.90 | MEN1 (0.72) | KMT2AMEN1MAPTLMNAHTT | |
| SCHEMBL31206219 | 0.90 | MEN1 (0.72) | KMT2AMEN1MAPTLMNAHTT | |
| SCHEMBL10344695 | 0.89 | MEN1 (1.00) | KMT2AMEN1MAPTLMNAHTT | |
| SCHEMBL29533340 | 0.89 | MEN1 (1.00) | KMT2AMEN1MAPTLMNAHTT | |
| SCHEMBL13666033 | 0.89 | MEN1 (0.70) | KMT2AMEN1MAPTLMNAHTT | |
| SCHEMBL17079616 | 0.89 | DDX3X (0.79) | KMT2AMEN1MAPTLMNAHTT | |
| SCHEMBL6227015 | 0.89 | MEN1 (0.71) | KMT2AMEN1MAPTLMNAHTT | |
| SCHEMBL3336175 | 0.88 | KDM4E (1.00) | KMT2AMEN1MAPTLMNAHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009131384-A2 | PHARMACEUTICAL COMPOSITION FOR PREVENTING AND TREATING MALARIA, CONTAINING COMPOUNDS THAT INHIBIT PLASMEPSIN II ACTIVITY, AND METHOD OF TREATING MALARIA USING THE SAME | INDUSTRY FOUNDATION OF CHONNAM NATIONAL UNIVERSITY (KR) | 2009-10-29 | — | — | WO | claimed |
| WO-2009131384-A2 | PHARMACEUTICAL COMPOSITION FOR PREVENTING AND TREATING MALARIA, CONTAINING COMPOUNDS THAT INHIBIT PLASMEPSIN II ACTIVITY, AND METHOD OF TREATING MALARIA USING THE SAME | INDUSTRY FOUNDATION OF CHONNAM NATIONAL UNIVERSITY (KR) | 2009-10-29 | — | — | WO | disclosed |