Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 8/20 | 0.78 |
| ▸ | MAOA | P21397 | 1/20 | 0.69 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.54 |
| ▸ | HPGD | P15428 | 4/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.54 |
| ▸ | RAB9A | P51151 | 3/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.54 |
| ▸ | NPC1 | O15118 | 3/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 3/20 | 0.49 |
| ▸ | SLC16A3 | O15427 | 2/20 | 0.49 |
| ▸ | GLA | P06280 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | CA12 | O43570 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | CA3 | P07451 | 1/20 | 0.44 |
| ▸ | CA4 | P22748 | 1/20 | 0.44 |
| ▸ | CA6 | P23280 | 1/20 | 0.44 |
| ▸ | CA7 | P43166 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27750354 | 0.88 | MAOB (1.00) | MAOBMAOAALDH1A1HPGDKDM4E | |
| SCHEMBL16674813 | 0.84 | MAOB (0.73) | MAOBMAOAALDH1A1HPGDKDM4E | |
| SCHEMBL27771378 | 0.84 | MAOB (0.78) | MAOBMAOAALDH1A1HPGDKDM4E | |
| SCHEMBL16674815 | 0.84 | MAOB (0.72) | MAOBMAOAALDH1A1HPGDKDM4E | |
| SCHEMBL28918559 | 0.81 | KDM4E (0.61) | MAOBMAOAALDH1A1HPGDKDM4E | |
| 7-Cyclohexyloxycoumarin SCHEMBL28918560 | 0.80 | KDM4E (0.63) | MAOBMAOAALDH1A1HPGDKDM4E | |
| SCHEMBL16674814 | 0.79 | MAOB (0.65) | MAOBMAOAALDH1A1HPGDKDM4E | |
| SCHEMBL11829416 | 0.79 | ALDH1A1 (0.76) | MAOBMAOAALDH1A1HPGDKDM4E | |
| SCHEMBL2336577 | 0.76 | KDM4E (0.62) | MAOBALDH1A1HPGDKDM4ERAB9A | |
| SCHEMBL16674816 | 0.76 | MAOA (0.68) | MAOBMAOAALDH1A1HPGDKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115368333-B | Ibuprofen-coumarin skeleton-containing compound and application thereof | 湖北医药学院 | 2024-11-19 | — | — | CN | disclosed |