SCHEMBL31207264 — predicted protein targets

Predicted protein targets (top 15)

	gene	UniProt	supporting neighbours	confidence
▸	NNMT	P40261	1/20	0.39

▸	NR3C1	P04150	2/20	0.37

▸	LRRK2	Q5S007	3/20	0.35

▸	GAA	P10253	1/20	0.35

▸	SMN1; SMN2	Q16637	1/20	0.35

▸	LMNA	P02545	1/20	0.35

▸	KMT2A	Q03164	2/20	0.35

▸	MEN1	O00255	1/20	0.35

▸	PABPC1	P11940	1/20	0.35

▸	EGFR	P00533	2/20	0.34

▸	ERBB2	P04626	2/20	0.34

▸	ALDH1A1	P00352	2/20	0.34

▸	IDH1	O75874	2/20	0.34

▸	KDM4E	B2RXH2	1/20	0.33

▸	OXTR	P30559	1/20	0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL31099027	0.87	NNMT (0.37)	NNMTNR3C1LRRK2GAALMNA
SCHEMBL25314821	0.87	NNMT (0.37)	NNMTNR3C1LRRK2GAALMNA
SCHEMBL31421693	0.78	NNMT (0.42)	NNMTSMN1; SMN2KMT2AMEN1PABPC1
SCHEMBL24940727	0.78	MC4R (0.42)	NNMTSMN1; SMN2LMNAKMT2AMEN1
SCHEMBL24853327	0.78	NNMT (0.42)	NNMTLMNAKMT2AMEN1PABPC1
SCHEMBL24094501	0.78	NNMT (0.42)	NNMTLMNAKMT2AMEN1PABPC1
SCHEMBL24853342	0.78	NNMT (0.42)	NNMTSMN1; SMN2KMT2AMEN1PABPC1
SCHEMBL24853326	0.77	NNMT (0.41)	NNMTLMNAKMT2AMEN1PABPC1
SCHEMBL24094500	0.76	NNMT (0.40)	NNMTLMNAKMT2AMEN1PABPC1
SCHEMBL31207254	0.75	ALDH1A1 (0.39)	GAASMN1; SMN2LMNAKMT2AMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
WO-2024255412-A1	SPIRO HETEROCYCLIC COMPOUND AND USE THEREOF	广州必贝特医药股份有限公司	2024-12-19	—	—	WO	disclosed