Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NNMT | P40261 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 3/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 3/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.33 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.33 |
| ▸ | ERN1 | O75460 | 1/20 | 0.33 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.33 |
| ▸ | EDNRB | P24530 | 1/20 | 0.32 |
| ▸ | EDNRA | P25101 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25583848 | 0.90 | NNMT (0.40) | NNMTMEN1KMT2AMAPTFFAR4 | |
| SCHEMBL31207261 | 0.81 | POLB (0.39) | MEN1KMT2AMAPTFFAR4POLB | |
| SCHEMBL31099092 | 0.81 | POLB (0.39) | MEN1KMT2AMAPTFFAR4POLB | |
| SCHEMBL29002114 | 0.79 | MEN1 (0.41) | NNMTMEN1KMT2AMAPTFFAR4 | |
| SCHEMBL30318801 | 0.78 | NNMT (0.38) | NNMTMEN1KMT2AMAPTFFAR4 | |
| SCHEMBL26179805 | 0.77 | NNMT (0.40) | NNMTMEN1KMT2AMAPTFFAR4 | |
| SCHEMBL24094506 | 0.75 | CNR2 (0.40) | NNMTMEN1KMT2AMAPTFFAR4 | |
| SCHEMBL30318808 | 0.75 | CNR2 (0.40) | NNMTMEN1KMT2AMAPTFFAR4 | |
| SCHEMBL29002106 | 0.75 | GPBAR1 (0.37) | MEN1KMT2AGAANPSR1POLB | |
| SCHEMBL16472498 | 0.73 | ALOX5AP (0.39) | NNMTMEN1KMT2AMAPTFFAR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024255412-A1 | SPIRO HETEROCYCLIC COMPOUND AND USE THEREOF | 广州必贝特医药股份有限公司 | 2024-12-19 | — | — | WO | disclosed |