Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | KDM1A | O60341 | 2/20 | 0.36 |
| ▸ | KDM1B | Q8NB78 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | NOTUM | Q6P988 | 2/20 | 0.35 |
| ▸ | SCN9A | Q15858 | 5/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1315783 | 0.82 | NOTUM (0.40) | L3MBTL1POLBGAAALDH1A1CYP3A4 | |
| SCHEMBL28788679 | 0.79 | HSD17B10 (0.39) | SMN1; SMN2ALDH1A1CYP3A4CA2HSD17B10 | |
| SCHEMBL14850042 | 0.79 | PKM (0.41) | L3MBTL1POLBGAAHTTSMN1; SMN2 | |
| SCHEMBL28341702 | 0.78 | NOTUM (0.43) | L3MBTL1POLBGAAHTTSMN1; SMN2 | |
| SCHEMBL16387297 | 0.76 | KDM1A (0.38) | KDM1AKDM1B | |
| SCHEMBL15785464 | 0.76 | KDM1A (0.44) | KDM1AKDM1BALDH1A1SCN9A | |
| SCHEMBL14810800 | 0.75 | SMN1; SMN2 (0.42) | KDM1AKDM1BGAAHTTSMN1; SMN2 | |
| SCHEMBL15599160 | 0.75 | SCN9A (0.39) | KDM1AKDM1BSCN9A | |
| SCHEMBL30883525 | 0.75 | SMN1; SMN2 (0.42) | KDM1AKDM1BGAAHTTSMN1; SMN2 | |
| SCHEMBL16880501 | 0.75 | L3MBTL1 (0.39) | L3MBTL1POLBKDM1AKDM1BCYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4702021-A1 | COMPOUNDS CAPABLE OF MODULATING GPR65 | Pathios Therapeutics Limited (GB) | 2026-03-04 | — | — | EP | disclosed |
| WO-2024224064-A1 | COMPOUNDS CAPABLE OF MODULATING GPR65 | Pathios Therapeutics Limited (GB) | 2024-10-31 | — | — | WO | disclosed |