Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN9A | Q15858 | 1/20 | 0.43 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.41 |
| ▸ | WDR5 | P61964 | 2/20 | 0.41 |
| ▸ | RORC | P51449 | 2/20 | 0.40 |
| ▸ | PAICS | P22234 | 1/20 | 0.40 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.39 |
| ▸ | PTGES | O14684 | 5/20 | 0.38 |
| ▸ | PARP10 | Q53GL7 | 2/20 | 0.38 |
| ▸ | PARP15 | Q460N3 | 1/20 | 0.38 |
| ▸ | FABP4 | P15090 | 1/20 | 0.36 |
| ▸ | ALOX5AP | P20292 | 3/20 | 0.36 |
| ▸ | FEN1 | P39748 | 3/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30296510 | 0.95 | WDR5 (0.43) | SCN9AMAP4K4WDR5RORCPAICS | |
| SCHEMBL26460478 | 0.95 | WDR5 (0.43) | SCN9AMAP4K4WDR5RORCPAICS | |
| SCHEMBL31207448 | 0.86 | CNR1 (0.42) | WDR5PTGES | |
| SCHEMBL30296462 | 0.84 | TDO2 (0.43) | SCN9APAICSFFAR4ALOX5APFEN1 | |
| SCHEMBL30296156 | 0.83 | STIM1 (0.38) | SCN9AWDR5PAICSPTGESALOX5AP | |
| SCHEMBL26461251 | 0.83 | STIM1 (0.38) | SCN9AWDR5PAICSPTGESALOX5AP | |
| SCHEMBL31207452 | 0.83 | STIM1 (0.38) | SCN9AWDR5PAICSPTGESALOX5AP | |
| SCHEMBL31207488 | 0.83 | STIM1 (0.38) | SCN9AWDR5PAICSPTGESALOX5AP | |
| SCHEMBL31207415 | 0.83 | WDR5 (0.38) | SCN9AWDR5PAICSPTGES | |
| SCHEMBL30296607 | 0.81 | TDO2 (0.43) | SCN9APAICSFFAR4ALOX5APFEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4702021-A1 | COMPOUNDS CAPABLE OF MODULATING GPR65 | Pathios Therapeutics Limited (GB) | 2026-03-04 | — | — | EP | disclosed |
| WO-2024224064-A1 | COMPOUNDS CAPABLE OF MODULATING GPR65 | Pathios Therapeutics Limited (GB) | 2024-10-31 | — | — | WO | disclosed |