Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FLT3 | P36888 | 11/20 | 0.67 |
| ▸ | PDGFRB | P09619 | 4/20 | 0.67 |
| ▸ | KIT | P10721 | 2/20 | 0.67 |
| ▸ | ABL1 | P00519 | 1/20 | 0.67 |
| ▸ | BCR | P11274 | 1/20 | 0.67 |
| ▸ | SMAD3 | P84022 | 1/20 | 0.65 |
| ▸ | XDH | P47989 | 2/20 | 0.61 |
| ▸ | PDGFRA | P16234 | 2/20 | 0.58 |
| ▸ | CLK1 | P49759 | 1/20 | 0.55 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.55 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | HPGD | P15428 | 2/20 | 0.51 |
| ▸ | RAB9A | P51151 | 2/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.51 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL217022 | 1.00 | FLT3 (0.67) | FLT3PDGFRBKITABL1BCR | |
| SCHEMBL2815266 | 0.87 | FLT3 (0.56) | FLT3PDGFRBKITABL1BCR | |
| SCHEMBL30694751 | 0.83 | XDH (0.61) | PDGFRBXDHPDGFRAKDM4EALDH1A1 | |
| SCHEMBL31310313 | 0.83 | RAB9A (0.72) | FLT3PDGFRBXDHPDGFRAHRH4 | |
| SCHEMBL214096 | 0.83 | RAB9A (0.72) | FLT3PDGFRBXDHPDGFRAHRH4 | |
| SCHEMBL829213 | 0.83 | KDM4E (0.76) | FLT3PDGFRBKITABL1BCR | |
| SCHEMBL617200 | 0.82 | XDH (0.59) | FLT3PDGFRBXDHPDGFRAHRH4 | |
| SCHEMBL3963537 | 0.82 | F7 (0.66) | FLT3PDGFRBXDHHRH4RAB9A | |
| SCHEMBL217291 | 0.82 | XDH (0.63) | FLT3PDGFRBKITABL1BCR | |
| SCHEMBL1104006 | 0.82 | PDGFRB (0.77) | FLT3PDGFRBXDHPDGFRAKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118974040-A | N- (3- (benzo [ B ] thiophen-2-amido) -phenyl) -2, 3-dihydrobenzo [ B ] [1,4] dioxin-6-amide derivatives and related compounds as lactic acid/ATP production inhibitors for the treatment of cancer | 威马特股份公司 | 2024-11-15 | — | — | CN | disclosed |