SCHEMBL31208138

SCHEMBL31208138

Cc1cccc(N)c1C#N

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CD44 P16070 1/20 0.50
CYP1A2 P05177 1/20 0.50
CYP2C19 P33261 1/20 0.50
CYP3A4 P08684 2/20 0.46
TDP1 Q9NUW8 2/20 0.46
TSHR P16473 2/20 0.44
PIK3CA P42336 1/20 0.44
LMNA P02545 2/20 0.42
KDM4E B2RXH2 4/20 0.41
ALDH1A1 P00352 4/20 0.41
POLB P06746 1/20 0.41
GRM6 O15303 1/20 0.38
KDM1A O60341 1/20 0.36
ADORA2A P29274 3/20 0.36
HSD17B10 Q99714 2/20 0.36
ADORA1 P30542 2/20 0.36
ADRA2A P08913 1/20 0.36
HTT P42858 1/20 0.36
HPGD P15428 1/20 0.36
MAP2K2 P36507 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1143074 1.00 CD44 (0.50) CD44CYP1A2CYP2C19CYP3A4TDP1
SCHEMBL1398115 0.83 ALDH1A1 (0.43) CD44CYP1A2CYP2C19CYP3A4TDP1
SCHEMBL102473 0.83 CYP1A2 (0.59) CYP1A2CYP2C19TSHRLMNAKDM4E
SCHEMBL29993462 0.82 LMNA (0.51) CD44CYP1A2CYP2C19CYP3A4TDP1
SCHEMBL28349620 0.80 CYP1A2 (0.57) CYP1A2CYP2C19TSHRLMNAKDM4E
Ethane SCHEMBL2154002 0.80 CYP1A2 (0.57) CYP1A2CYP2C19TSHRLMNAKDM4E
Aniline SCHEMBL28030200 0.78 CYP1A2 (0.47) CYP1A2CYP2C19CYP3A4TDP1TSHR
SCHEMBL9131363 0.78 ALDH1A1 (0.57) CD44CYP1A2CYP2C19CYP3A4TDP1
SCHEMBL6149952 0.77 CD44 (0.50) CD44CYP1A2CYP2C19CYP3A4TDP1
SCHEMBL1702636 0.74 CYP3A4 (0.48) CYP1A2CYP2C19CYP3A4TDP1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118919857-A Electrolyte for improving low-temperature performance and lithium ion battery 合肥国轩高科动力能源有限公司 2024-11-08 CN disclosed