Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.32 |
| ▸ | KHK | P50053 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | ARG1 | P05089 | 1/20 | 0.31 |
| ▸ | ARG2 | P78540 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12120282 | 1.00 | HTR6 (0.43) | HTR6ALDH1A1KDM4EKMT2APKM | |
| Bromide SCHEMBL1307212 | 0.98 | HTR6 (0.42) | HTR6ALDH1A1KDM4EKMT2APKM | |
| SCHEMBL2226268 | 0.89 | KDM4E (0.39) | ALDH1A1KDM4EKMT2APKMSLC18A3 | |
| Hydrochloric Acid SCHEMBL12806190 | 0.87 | KDM4E (0.38) | ALDH1A1KDM4EKMT2APKMSLC18A3 | |
| SCHEMBL23269702 | 0.86 | KDM4E (0.37) | ALDH1A1KDM4EKMT2APKMSLC18A3 | |
| SCHEMBL3957401 | 0.85 | KDM4E (0.42) | ALDH1A1KDM4EKMT2APKMSLC18A3 | |
| SCHEMBL639712 | 0.82 | HTR6 (0.43) | HTR6ALDH1A1SMN1; SMN2KHK | |
| SCHEMBL639711 | 0.82 | HTR6 (0.43) | HTR6ALDH1A1SMN1; SMN2KHK | |
| SCHEMBL31209974 | 0.78 | HTR6 (0.40) | HTR6KMT2AHSD11B1KHKMEN1 | |
| SCHEMBL20577428 | 0.78 | HTR6 (0.46) | HTR6KHK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240368193-A1 | KRAS INHIBITORS | ELI LILLY AND COMPANY | 2024-11-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240368193-A1 | KRAS INHIBITORS | KRAS, NRAS, HRAS | HTR6 4845/4885ALDH1A1 2134/4885KDM4E 2107/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.