SCHEMBL20577428

SCHEMBL20577428

ICN1CCN(C2CCNC2)CC1

nearest known ligand 0.46

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
HTR6 P50406 1/20 0.46
KHK P50053 4/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4665502 0.88 HPGD (0.33) HTR6KHK
SCHEMBL31208735 0.81 HTR6 (0.46) HTR6KHK
SCHEMBL31208773 0.81 HTR6 (0.46) HTR6KHK
SCHEMBL27063781 0.79 HTR6 (0.44) HTR6
SCHEMBL31208620 0.79 HTR6 (0.56) HTR6KHK
SCHEMBL1400723 0.79 HTR6 (0.56) HTR6KHK
SCHEMBL29316993 0.79 HTR6 (0.56) HTR6KHK
SCHEMBL639712 0.78 HTR6 (0.43) HTR6KHK
SCHEMBL18672319 0.78 HTR6 (0.52) HTR6KHK
SCHEMBL31209005 0.78 HTR6 (0.43) HTR6KHK

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3630779-A1 ANTIBIOTIC RESISTANCE BREAKERS Kings College London (GB) 2020-04-08 EP disclosed
WO-2018220365-A1 ANTIBIOTIC RESISTANCE BREAKERS KING'S COLLEGE LONDON (GB) 2018-12-06 WO disclosed