Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GOT1 | P17174 | 2/20 | 0.46 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.43 |
| ▸ | BACE1 | P56817 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | JAK1 | P23458 | 3/20 | 0.41 |
| ▸ | JAK2 | O60674 | 1/20 | 0.41 |
| ▸ | TYK2 | P29597 | 1/20 | 0.41 |
| ▸ | JAK3 | P52333 | 1/20 | 0.41 |
| ▸ | BTK | Q06187 | 2/20 | 0.40 |
| ▸ | KIT | P10721 | 1/20 | 0.40 |
| ▸ | EED | O75530 | 1/20 | 0.39 |
| ▸ | RBBP4 | Q09028 | 1/20 | 0.39 |
| ▸ | SUZ12 | Q15022 | 1/20 | 0.39 |
| ▸ | EZH2 | Q15910 | 1/20 | 0.39 |
| ▸ | AEBP2 | Q6ZN18 | 1/20 | 0.39 |
| ▸ | NAMPT | P43490 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | BRD4 | O60885 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31210541 | 0.89 | GOT1 (0.47) | GOT1BACE1ALDH1A1LMNAMAPT | |
| SCHEMBL5704985 | 0.84 | GOT1 (0.45) | GOT1BACE1ALDH1A1LMNAMAPT | |
| SCHEMBL5704854 | 0.83 | MAPT (0.46) | GOT1BACE1ALDH1A1LMNAMAPT | |
| SCHEMBL5704915 | 0.83 | DRD2 (0.50) | GOT1BACE1ALDH1A1LMNAMAPT | |
| SCHEMBL25102966 | 0.79 | NR1H2 (0.42) | NR1H2BACE1ALDH1A1LMNAMAPT | |
| SCHEMBL25337613 | 0.78 | BACE1 (0.44) | GOT1BACE1ALDH1A1LMNAMAPT | |
| SCHEMBL16336702 | 0.78 | JAK1 (0.49) | ALDH1A1MAPTJAK1JAK2TYK2 | |
| SCHEMBL3723331 | 0.78 | JAK1 (0.51) | NR1H2ALDH1A1MAPTJAK1JAK2 | |
| SCHEMBL31211125 | 0.77 | BTK (0.39) | GOT1ALDH1A1LMNAMAPTJAK1 | |
| SCHEMBL2428090 | 0.77 | PIM3 (0.47) | ALDH1A1LMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024182778-A1 | COMPOUNDS AND METHODS FOR MODULATING SPLICING | REMIX THERAPEUTICS INC. (US) | 2024-09-06 | — | — | WO | disclosed |