Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 1/20 | 0.38 |
| ▸ | ASGR1 | P07306 | 1/20 | 0.34 |
| ▸ | KDM4D | Q6B0I6 | 1/20 | 0.34 |
| ▸ | PPM1D | O15297 | 1/20 | 0.33 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.31 |
| ▸ | KAT6A | Q92794 | 1/20 | 0.30 |
| ▸ | KAT8 | Q9H7Z6 | 1/20 | 0.30 |
| ▸ | SPR | P35270 | 1/20 | 0.30 |
| ▸ | JAK2 | O60674 | 1/20 | 0.30 |
| ▸ | JAK1 | P23458 | 1/20 | 0.30 |
| ▸ | JAK3 | P52333 | 1/20 | 0.30 |
| ▸ | BUB1 | O43683 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31071235 | 0.85 | HSD11B1 (0.38) | HSD11B1ASGR1KDM4DPPM1DKAT8 | |
| SCHEMBL190837 | 0.82 | HSD11B1 (0.47) | HSD11B1ASGR1KDM4DPDE10AKAT6A | |
| SCHEMBL13052385 | 0.80 | PPM1D (0.32) | PPM1D | |
| SCHEMBL12548366 | 0.80 | HSD11B1 (0.41) | HSD11B1ASGR1KDM4DPDE10AKAT6A | |
| SCHEMBL1057481 | 0.80 | HSD11B1 (0.41) | HSD11B1ASGR1KDM4DPDE10AKAT6A | |
| SCHEMBL1057478 | 0.80 | HSD11B1 (0.41) | HSD11B1ASGR1KDM4DPDE10AKAT6A | |
| SCHEMBL7808569 | 0.79 | HSD11B1 (0.36) | HSD11B1ASGR1KDM4D | |
| SCHEMBL4974713 | 0.78 | PPM1D (0.31) | PPM1D | |
| SCHEMBL4974716 | 0.78 | PPM1D (0.31) | PPM1D | |
| SCHEMBL1584306 | 0.78 | PPM1D (0.31) | PPM1D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024182778-A1 | COMPOUNDS AND METHODS FOR MODULATING SPLICING | REMIX THERAPEUTICS INC. (US) | 2024-09-06 | — | — | WO | disclosed |