Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 1/20 | 0.36 |
| ▸ | KDM4D | Q6B0I6 | 1/20 | 0.34 |
| ▸ | ASGR1 | P07306 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7816804 | 0.80 | HSD11B1 (0.40) | HSD11B1KDM4DASGR1 | |
| SCHEMBL31211348 | 0.79 | HSD11B1 (0.38) | HSD11B1KDM4DASGR1 | |
| SCHEMBL190837 | 0.79 | HSD11B1 (0.47) | HSD11B1KDM4DASGR1 | |
| SCHEMBL23841944 | 0.78 | HSD11B1 (0.40) | HSD11B1KDM4DASGR1 | |
| SCHEMBL28804055 | 0.74 | HSD11B1 (0.44) | HSD11B1KDM4DASGR1 | |
| SCHEMBL28804053 | 0.74 | HSD11B1 (0.44) | HSD11B1KDM4DASGR1 | |
| SCHEMBL228179 | 0.74 | HSD11B1 (0.46) | HSD11B1KDM4DASGR1 | |
| SCHEMBL17173156 | 0.73 | HSD11B1 (0.41) | HSD11B1KDM4DASGR1 | |
| SCHEMBL17173155 | 0.73 | HSD11B1 (0.41) | HSD11B1KDM4DASGR1 | |
| SCHEMBL1958715 | 0.73 | HSD11B1 (0.43) | HSD11B1KDM4DASGR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0798298-B1 | THIAZOLIDINONE OR OXAZOLIDINONE DERIVATIVES TO TREAT ANGINA PECTORIS OR COMPOSITIONS CONTAINING THE SAME AS ACTIVE INGREDIENT | SANKYO CO (JP) | 2001-08-08 | — | — | EP | disclosed |
| US-5843973-A | Thiazolidinone compounds and composition for angina pectoris comprising the compounds as an active ingredient | SANKYO COMPANY, LIMITED (JP) | 1998-12-01 | — | — | US | disclosed |
| EP-0798298-A1 | THIAZOLIDINONE COMPOUNDS OR ANGINA PECTORIS REMEDY OR PREVENTIVE CONTAINING THE SAME AS ACTIVE INGREDIENT | SANKYO COMPANY LIMITED (JP) | 1997-10-01 | — | — | EP | disclosed |