Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | KCNQ3 | O43525 | 3/20 | 0.35 |
| ▸ | KCNQ2 | O43526 | 3/20 | 0.35 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.35 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.35 |
| ▸ | TNKS | O95271 | 1/20 | 0.35 |
| ▸ | PIK3CD | O00329 | 3/20 | 0.34 |
| ▸ | PIK3CG | P48736 | 3/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | PIK3R2 | O00459 | 1/20 | 0.34 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.34 |
| ▸ | PIK3CB | P42338 | 2/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | HTR3A | P46098 | 3/20 | 0.33 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31211879 | 0.93 | HTR3A (0.37) | HPGDSMN1; SMN2ALDH1A1APOBEC3AAPOBEC3G | |
| SCHEMBL31211872 | 0.83 | KDM4E (0.41) | HPGDSMN1; SMN2ALDH1A1HTR3APDE2A | |
| SCHEMBL31211868 | 0.77 | KDM4E (0.39) | HPGDALDH1A1HTR3APDE2A | |
| SCHEMBL31211913 | 0.75 | IRAK4 (0.41) | APOBEC3AAPOBEC3GMEN1KMT2AL3MBTL1 | |
| SCHEMBL30408161 | 0.74 | IRAK4 (0.40) | HPGDSMN1; SMN2APOBEC3AAPOBEC3GPIK3CA | |
| SCHEMBL31211922 | 0.74 | APOBEC3A (0.38) | HPGDSMN1; SMN2ALDH1A1KCNQ3KCNQ2 | |
| SCHEMBL31211802 | 0.74 | L3MBTL1 (0.36) | HPGDALDH1A1KCNQ3KCNQ2APOBEC3A | |
| SCHEMBL31211952 | 0.74 | L3MBTL1 (0.36) | HPGDSMN1; SMN2ALDH1A1KCNQ3KCNQ2 | |
| SCHEMBL25338101 | 0.74 | SMPD3 (0.46) | KCNQ3KCNQ2APOBEC3AAPOBEC3GMEN1 | |
| SCHEMBL31211998 | 0.74 | SMPD3 (0.42) | KCNQ3KCNQ2APOBEC3AAPOBEC3GMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118973581-A | IRAK degradation agent and application thereof | 凯麦拉医疗公司 | 2024-11-15 | — | — | CN | disclosed |