Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CD274 | Q9NZQ7 | 8/20 | 0.42 |
| ▸ | PDCD1 | Q15116 | 7/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.38 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | RET | P07949 | 1/20 | 0.37 |
| ▸ | OGA | O60502 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31213169 | 0.81 | CD274 (0.44) | CD274PDCD1L3MBTL1TDP1SMN1; SMN2 | |
| SCHEMBL31213192 | 0.75 | L3MBTL1 (0.44) | CD274PDCD1L3MBTL1TDP1NPC1 | |
| SCHEMBL6845658 | 0.73 | VHL (0.47) | MAPTCYP11B1CYP11B2 | |
| SCHEMBL31213188 | 0.73 | PDCD1 (0.56) | CD274PDCD1 | |
| SCHEMBL31213228 | 0.71 | CD274 (0.39) | CD274PDCD1L3MBTL1TDP1SMN1; SMN2 | |
| SCHEMBL31213241 | 0.70 | CD274 (0.56) | CD274PDCD1L3MBTL1TDP1 | |
| SCHEMBL31213184 | 0.70 | PDCD1 (0.62) | CD274PDCD1L3MBTL1TDP1 | |
| SCHEMBL11910286 | 0.69 | MAPT (0.47) | CD274PDCD1MAPTNPC1RAB9A | |
| SCHEMBL31213199 | 0.69 | CD274 (0.42) | CD274PDCD1L3MBTL1TDP1 | |
| SCHEMBL31213242 | 0.69 | CD274 (0.49) | CD274PDCD1SMN1; SMN2KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240336601-A1 | 4-PHENYL-INDOLE DERIVATIVES AND RELATED USES | CHULALONG UNIVERSITY (TH) | 2024-10-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240336601-A1 | 4-PHENYL-INDOLE DERIVATIVES AND RELATED USES | PDCD1, PDCD1LG2, CD274 | CD274 3/4885PDCD1 1/4885MAPT 3152/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.