Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | VHL | P40337 | 1/20 | 0.47 |
| ▸ | CYP17A1 | P05093 | 2/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.45 |
| ▸ | DHPS | P49366 | 1/20 | 0.44 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.42 |
| ▸ | CDC7 | O00311 | 1/20 | 0.41 |
| ▸ | CDK2 | P24941 | 1/20 | 0.41 |
| ▸ | CYP11B2 | P19099 | 3/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | RPS6KA5 | O75582 | 1/20 | 0.39 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.39 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.38 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.38 |
| ▸ | P4HTM | Q9NXG6 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6846191 | 0.82 | DHPS (0.50) | CYP1A2DHPSMAPK14MAPTCYP2A6 | |
| SCHEMBL6846105 | 0.82 | MAPK14 (0.49) | CYP17A1CYP1A2DHPSMAPK14MAPT | |
| SCHEMBL6846190 | 0.78 | DHPS (0.44) | CYP17A1CYP1A2DHPSMAPK14MAPT | |
| SCHEMBL6847772 | 0.78 | DYRK1A (0.47) | CYP17A1CYP1A2DHPSMAPK14MAPT | |
| SCHEMBL7021321 | 0.77 | MAPT (0.44) | CYP17A1CYP1A2DHPSMAPK14MAPT | |
| SCHEMBL6661647 | 0.75 | MAPK14 (0.44) | CYP17A1CYP1A2DHPSMAPK14MAPT | |
| SCHEMBL6658639 | 0.75 | MAPK14 (0.43) | CYP17A1CYP1A2MAPK14MAPTCYP2A6 | |
| SCHEMBL6663847 | 0.74 | MAPK14 (0.43) | CYP1A2DHPSMAPK14MAPTCDC7 | |
| SCHEMBL6659220 | 0.74 | CYP11B1 (0.53) | VHLCYP17A1MAPTCYP2A6CYP11B2 | |
| SCHEMBL31213232 | 0.73 | CD274 (0.42) | MAPTCYP11B2CYP11B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040236110-A1 | Substituted 3-pyridyl indoles and indazoles as c17,20 lyase inhibitors | BAYER PHARMACEUTICALS CORPORATION | 2004-11-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040236110-A1 | Substituted 3-pyridyl indoles and indazoles as c17,20 lyase inhibitors | CYP17A1, IDO1, CYP21A2 | VHL 1892/4885CYP17A1 1/4885CYP1A2 32/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.