Known targets — ChEMBL curated mechanism
ACHECHKACHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNB1CHRNDCHRNECHRNGHRH2OPRM1
The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.43 |
| ▸ | CALM1 | P0DP23 | 1/20 | 0.41 |
| ▸ | IDO1 | P14902 | 1/20 | 0.38 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | MAOB | P27338 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.36 |
| ▸ | CASP1 | P29466 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.36 |
| ▸ | MAOA | P21397 | 1/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1357485 | 0.95 | TSHR (0.48) | TSHRALDH1A1TP53TRPA1CALM1 | |
| Hydrochloric Acid SCHEMBL30473262 | 0.92 | TSHR (0.46) | TSHRALDH1A1TP53TRPA1CALM1 | |
| Bromide SCHEMBL8601709 | 0.92 | TSHR (0.46) | TSHRALDH1A1TP53TRPA1CALM1 | |
| Bromide SCHEMBL28096513 | 0.90 | TSHR (0.43) | TSHRALDH1A1TP53TRPA1CALM1 | |
| Bromide SCHEMBL28096512 | 0.90 | TSHR (0.43) | TSHRALDH1A1TP53TRPA1CALM1 | |
| SCHEMBL9007220 | 0.78 | TP53 (0.48) | TSHRALDH1A1TP53TRPA1CALM1 | |
| SCHEMBL29637107 | 0.76 | TP53 (0.46) | TSHRALDH1A1TP53TRPA1CALM1 | |
| SCHEMBL4449680 | 0.76 | MEN1 (0.36) | TSHRALDH1A1TP53TRPA1IDO1 | |
| SCHEMBL9122338 | 0.74 | TP53 (0.43) | TSHRALDH1A1TP53TRPA1CALM1 | |
| SCHEMBL15285891 | 0.74 | TP53 (0.43) | TSHRALDH1A1TP53TRPA1CALM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118994261-A | Aryl-containing substituted tetrahydronaphthol-phosphine complex and preparation method and application thereof | 中国石油化工股份有限公司 | 2024-11-22 | — | — | CN | claimed |
| CN-118994260-A | Tetrahydronaphthol-phosphine late transition metal complex, and preparation method and application thereof | 中国石油化工股份有限公司 | 2024-11-22 | — | — | CN | claimed |
| CN-118620001-A | Metal organic complex and preparation method and application thereof | 中国石油化工股份有限公司 | 2024-09-10 | — | — | CN | claimed |
| CN-119798493-A | Coordination precipitation polymerization process for olefin polymerization and polyolefin | 中国石油化工股份有限公司 | 2025-04-11 | — | — | CN | disclosed |
| CN-119661749-A | Coordination precipitation polymerization process for olefin polymerization and polyolefin | 中国石油化工股份有限公司 | 2025-03-21 | — | — | CN | disclosed |
| CN-118994260-A | Tetrahydronaphthol-phosphine late transition metal complex, and preparation method and application thereof | 中国石油化工股份有限公司 | 2024-11-22 | — | — | CN | disclosed |
| CN-118994261-A | Aryl-containing substituted tetrahydronaphthol-phosphine complex and preparation method and application thereof | 中国石油化工股份有限公司 | 2024-11-22 | — | — | CN | disclosed |
| CN-118620001-A | Metal organic complex and preparation method and application thereof | 中国石油化工股份有限公司 | 2024-09-10 | — | — | CN | disclosed |