Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | LMNA | P02545 | 3/20 | 0.51 |
| ▸ | MAPT | P10636 | 6/20 | 0.49 |
| ▸ | THRB | P10828 | 1/20 | 0.47 |
| ▸ | DPP4 | P27487 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | ACHE | P22303 | 1/20 | 0.40 |
| ▸ | SLC6A5 | Q9Y345 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29772108 | 0.85 | ALDH1A1 (0.55) | ALDH1A1KMT2ALMNAMAPTTHRB | |
| SCHEMBL3216240 | 0.83 | ALDH1A1 (0.60) | ALDH1A1KMT2ALMNAMAPTTHRB | |
| SCHEMBL3201980 | 0.82 | ALDH1A1 (0.59) | ALDH1A1KMT2ALMNAMAPTTHRB | |
| SCHEMBL25845426 | 0.82 | ALDH1A1 (0.62) | ALDH1A1KMT2ALMNAMAPTTHRB | |
| SCHEMBL29772056 | 0.82 | ALDH1A1 (0.59) | ALDH1A1KMT2ALMNAMAPTTHRB | |
| SCHEMBL31216628 | 0.81 | ALDH1A1 (0.45) | ALDH1A1KMT2ALMNAMAPTTHRB | |
| SCHEMBL27194314 | 0.81 | ALDH1A1 (0.57) | ALDH1A1KMT2ALMNAMAPTTHRB | |
| SCHEMBL23783030 | 0.80 | ALDH1A1 (0.60) | ALDH1A1KMT2ALMNAMAPTTHRB | |
| SCHEMBL31216639 | 0.80 | ALDH1A1 (0.56) | ALDH1A1KMT2ALMNAMAPTTHRB | |
| SCHEMBL29772106 | 0.80 | ALDH1A1 (0.56) | ALDH1A1KMT2ALMNAMAPTTHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024208256-A1 | TARGETED PROTEIN DEGRADATION COMPOUND AND PREPARATION METHOD THEREFOR AND USE THEREOF | 上海汇伦医药股份有限公司 | 2024-10-10 | — | — | WO | disclosed |