Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | MAPT | P10636 | 3/20 | 0.45 |
| ▸ | GFER | P55789 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 4/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | ACACB | O00763 | 8/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.34 |
| ▸ | DPP4 | P27487 | 1/20 | 0.34 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.34 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.34 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31216596 | 0.81 | ALDH1A1 (0.52) | ALDH1A1MAPTLMNAMAPK1TDP1 | |
| SCHEMBL25845423 | 0.79 | ALDH1A1 (0.51) | ALDH1A1MAPTGFERLMNAMAPK1 | |
| SCHEMBL25584570 | 0.78 | MAPT (0.50) | ALDH1A1MAPTGFERLMNAMAPK1 | |
| SCHEMBL23823282 | 0.77 | ALDH1A1 (0.49) | ALDH1A1MAPTGFERLMNAMAPK1 | |
| SCHEMBL20231853 | 0.76 | MAPT (0.54) | ALDH1A1MAPTGFERLMNAMAPK1 | |
| SCHEMBL29890862 | 0.76 | MAPT (0.54) | ALDH1A1MAPTGFERLMNAMAPK1 | |
| SCHEMBL30207450 | 0.74 | GPR119 (0.51) | SMN1; SMN2DPP4 | |
| SCHEMBL3028930 | 0.74 | ALDH1A1 (0.69) | ALDH1A1MAPTGFERLMNAMAPK1 | |
| SCHEMBL29990084 | 0.74 | ALDH1A1 (0.69) | ALDH1A1MAPTGFERLMNAMAPK1 | |
| SCHEMBL24735237 | 0.74 | ALDH1A1 (0.48) | ALDH1A1MAPTGFERLMNAMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024208256-A1 | TARGETED PROTEIN DEGRADATION COMPOUND AND PREPARATION METHOD THEREFOR AND USE THEREOF | 上海汇伦医药股份有限公司 | 2024-10-10 | — | — | WO | disclosed |