Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.47 |
| ▸ | GPR119 | Q8TDV5 | 10/20 | 0.46 |
| ▸ | MGLL | Q99685 | 1/20 | 0.43 |
| ▸ | NAMPT | P43490 | 4/20 | 0.41 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.41 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2547209 | 0.87 | GPR119 (0.56) | USP30GPR119AAK1HRH3 | |
| SCHEMBL31496265 | 0.85 | USP30 (0.54) | USP30GPR119MGLLNAMPT | |
| SCHEMBL16491261 | 0.85 | USP30 (0.51) | USP30GPR119AAK1HRH3 | |
| SCHEMBL30801988 | 0.85 | GPR119 (0.48) | USP30GPR119MGLLNAMPTHRH3 | |
| SCHEMBL30801985 | 0.85 | GPR119 (0.47) | USP30GPR119MGLLNAMPTAAK1 | |
| SCHEMBL16015060 | 0.83 | USP30 (0.57) | USP30GPR119AAK1HRH3 | |
| SCHEMBL15477472 | 0.83 | USP30 (0.57) | USP30GPR119AAK1HRH3 | |
| SCHEMBL2549323 | 0.83 | USP30 (0.57) | USP30GPR119AAK1HRH3 | |
| SCHEMBL17393897 | 0.82 | USP30 (0.53) | USP30GPR119AAK1HRH3 | |
| SCHEMBL29963696 | 0.82 | USP30 (0.53) | USP30GPR119AAK1HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024208256-A1 | TARGETED PROTEIN DEGRADATION COMPOUND AND PREPARATION METHOD THEREFOR AND USE THEREOF | 上海汇伦医药股份有限公司 | 2024-10-10 | — | — | WO | disclosed |