Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 7/20 | 0.47 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.43 |
| ▸ | MGLL | Q99685 | 1/20 | 0.40 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.39 |
| ▸ | PDE4D | Q08499 | 3/20 | 0.39 |
| ▸ | PDE4A | P27815 | 2/20 | 0.39 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.39 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.39 |
| ▸ | BACE1 | P56817 | 1/20 | 0.39 |
| ▸ | BACE2 | Q9Y5Z0 | 1/20 | 0.39 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.39 |
| ▸ | KDM1A | O60341 | 1/20 | 0.38 |
| ▸ | NAMPT | P43490 | 2/20 | 0.38 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13717948 | 0.89 | GPR119 (0.58) | GPR119USP30ROCK1PDE4DPDE4A | |
| SCHEMBL31216632 | 0.85 | USP30 (0.47) | GPR119USP30MGLLNAMPTAAK1 | |
| SCHEMBL30490303 | 0.83 | GPR119 (0.54) | GPR119MGLLPDE4DPDE4APDE4B | |
| SCHEMBL30801988 | 0.82 | GPR119 (0.48) | GPR119USP30MGLLHDAC2HDAC1 | |
| SCHEMBL30801945 | 0.82 | GPR119 (0.52) | GPR119USP30PDE4DPDE4APDE4B | |
| SCHEMBL23150520 | 0.81 | GPR119 (0.51) | GPR119MGLLPDE4DPDE4APDE4B | |
| SCHEMBL31496265 | 0.81 | USP30 (0.54) | GPR119USP30MGLLNAMPT | |
| SCHEMBL1474406 | 0.79 | KDM1A (0.49) | GPR119MGLLHDAC2HDAC1KDM1A | |
| SCHEMBL18825434 | 0.79 | USP30 (0.49) | GPR119USP30ROCK1AAK1 | |
| SCHEMBL31498784 | 0.79 | CYP11B2 (0.48) | GPR119USP30ROCK1BACE1BACE2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024054603-A1 | HETEROBIFUNCTIONAL COMPOUNDS AND METHODS OF TREATING DISEASE | HALDA THERAPEUTICS OPCO, INC. (US) | 2024-03-14 | — | — | WO | disclosed |