Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | XDH | P47989 | 9/20 | 0.72 |
| ▸ | TARBP2 | Q15633 | 2/20 | 0.72 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.72 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.72 |
| ▸ | PGR | P06401 | 1/20 | 0.72 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.72 |
| ▸ | PDE4A | P27815 | 1/20 | 0.72 |
| ▸ | BLVRB | P30043 | 1/20 | 0.72 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.72 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.72 |
| ▸ | PPID | Q08752 | 1/20 | 0.65 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.47 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.46 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31307441 | 0.88 | XDH (0.81) | XDHTARBP2ABCC4ABCB11PGR | |
| SCHEMBL2635992 | 0.85 | XDH (0.83) | XDHTARBP2ABCC4ABCB11PGR | |
| SCHEMBL29323469 | 0.84 | XDH (0.81) | XDHTARBP2ABCC4ABCB11PGR | |
| Febuxostat SCHEMBL249339 | 0.84 | XDH (1.00) | XDHTARBP2ABCC4ABCB11PGR | |
| Febuxostat SCHEMBL29398803 | 0.84 | XDH (1.00) | XDHTARBP2ABCC4ABCB11PGR | |
| Febuxostat SCHEMBL28271887 | 0.84 | XDH (1.00) | XDHTARBP2ABCC4ABCB11PGR | |
| SCHEMBL16363788 | 0.84 | XDH (0.85) | XDHTARBP2ABCC4ABCB11PGR | |
| Febuxostat SCHEMBL30161803 | 0.84 | XDH (1.00) | XDHTARBP2ABCC4ABCB11PGR | |
| SCHEMBL22745199 | 0.84 | XDH (0.78) | XDHTARBP2ABCC4ABCB11PGR | |
| SCHEMBL22745342 | 0.84 | XDH (0.78) | XDHTARBP2ABCC4ABCB11PGR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118994140-A | Triazole derivative with antidepressant effect, and preparation method and application thereof | 河南科技大学 | 2024-11-22 | — | — | CN | disclosed |