Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 2/20 | 0.31 |
| ▸ | RAB9A | P51151 | 2/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.31 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.31 |
| ▸ | NSD1 | Q96L73 | 1/20 | 0.31 |
| ▸ | NQO2 | P16083 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
| ▸ | PKM | P14618 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28386183 | 1.00 | HSD17B10 (0.36) | HSD17B10MAPTKDM4ENPC1RAB9A | |
| SCHEMBL15985836 | 0.81 | MAPT (0.45) | HSD17B10MAPTKDM4ENPC1RAB9A | |
| SCHEMBL20582165 | 0.78 | HSD17B10 (0.61) | HSD17B10MAPTNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL18281921 | 0.78 | ALDH1A1 (0.40) | HSD17B10MAPTKDM4ENPC1RAB9A | |
| SCHEMBL31218402 | 0.78 | HSD17B10 (0.61) | HSD17B10MAPTNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL9032146 | 0.75 | HSD17B10 (0.44) | HSD17B10MAPTKDM4ENPC1RAB9A | |
| SCHEMBL15982388 | 0.75 | MAPT (0.33) | HSD17B10MAPTKDM4E | |
| SCHEMBL28384381 | 0.71 | MAPT (0.40) | HSD17B10MAPTKDM4ENPC1RAB9A | |
| SCHEMBL21683098 | 0.71 | HSD17B10 (0.44) | HSD17B10MAPTKDM4ENPC1RAB9A | |
| SCHEMBL18281990 | 0.70 | KDM4E (0.35) | HSD17B10MAPTKDM4ENPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111065626-B | Compounds for the treatment of huntington's disease | PTC医疗公司 | 2024-09-27 | — | — | CN | disclosed |