Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 7/20 | 0.47 |
| ▸ | MAOA | P21397 | 4/20 | 0.36 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | CASP1 | P29466 | 1/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | CASP7 | P55210 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | RET | P07949 | 4/20 | 0.35 |
| ▸ | F3 | P13726 | 1/20 | 0.34 |
| ▸ | MIF | P14174 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.33 |
| ▸ | FLT3 | P36888 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28129799 | 0.80 | MAOB (0.43) | MAOBMAOACYP19A1CYP1A2HPGD | |
| SCHEMBL31219512 | 0.76 | GSK3B (0.46) | HPGDGAAMAPTNPSR1LMNA | |
| SCHEMBL15651220 | 0.73 | RPS6KA3 (0.31) | RPS6KA3 | |
| SCHEMBL16427344 | 0.68 | KDR (0.49) | MAOBMAOACYP19A1 | |
| SCHEMBL16427343 | 0.68 | KDR (0.49) | MAOBMAOACYP19A1 | |
| SCHEMBL16426717 | 0.68 | MAOB (0.48) | MAOBMAOACYP19A1 | |
| SCHEMBL16426716 | 0.68 | MAOB (0.48) | MAOBMAOACYP19A1 | |
| SCHEMBL16426516 | 0.68 | ELANE (0.43) | MAOBMAOAHPGDKDM4EMAPT | |
| SCHEMBL16426515 | 0.68 | ELANE (0.43) | MAOBMAOAHPGDKDM4EMAPT | |
| SCHEMBL31219495 | 0.68 | LRRK2 (0.69) | RETPDPK1FLT3ALKRPS6KA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118754878-A | Quinazoline derivative with broad-spectrum anti-tumor activity as well as preparation method and application thereof | 成都安博力善生物科技有限公司 | 2024-10-11 | — | — | CN | claimed |
| CN-118754878-A | Quinazoline derivative with broad-spectrum anti-tumor activity as well as preparation method and application thereof | 成都安博力善生物科技有限公司 | 2024-10-11 | — | — | CN | disclosed |