Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 1/20 | 0.43 |
| ▸ | ACHE | P22303 | 3/20 | 0.39 |
| ▸ | BCHE | P06276 | 2/20 | 0.39 |
| ▸ | LTA4H | P09960 | 1/20 | 0.37 |
| ▸ | CALM1 | P0DP23 | 1/20 | 0.36 |
| ▸ | PARP11 | Q9NR21 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | MAOB | P27338 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | MIF | P14174 | 1/20 | 0.33 |
| ▸ | MAOA | P21397 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16426515 | 1.00 | ELANE (0.43) | ELANEACHEBCHELTA4HCALM1 | |
| SCHEMBL28129799 | 0.85 | MAOB (0.43) | LMNAMAPTKMT2AALDH1A1MAPK1 | |
| SCHEMBL16427344 | 0.80 | KDR (0.49) | BCHEMAOBMAOA | |
| SCHEMBL16426716 | 0.80 | MAOB (0.48) | MAOBMAOA | |
| SCHEMBL16427343 | 0.80 | KDR (0.49) | BCHEMAOBMAOA | |
| SCHEMBL16426717 | 0.80 | MAOB (0.48) | MAOBMAOA | |
| SCHEMBL16426758 | 0.77 | RAB9A (0.55) | ACHEBCHELTA4HLMNAMAPT | |
| SCHEMBL16426757 | 0.77 | RAB9A (0.55) | ACHEBCHELTA4HLMNAMAPT | |
| SCHEMBL27755298 | 0.76 | MAPT (0.52) | ELANELMNAMAPTKMT2AALDH1A1 | |
| SCHEMBL16426828 | 0.70 | CYP1A2 (0.49) | MAPTMAOBMAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20150038543-A1 | ANTI-GLYCATION PROPERTIES OF OXINDOLE DERIVATIVES | CHOUDHARY MUHAMMAD IQBAL (PK) | 2015-02-05 | — | — | US | disclosed |