Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 8/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | RAB9A | P51151 | 3/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.36 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.36 |
| ▸ | RELA | Q04206 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 3/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31222092 | 0.92 | GAA (0.43) | GAAALDH1A1MAPTCYP1A2CYP2C9 | |
| SCHEMBL31222125 | 0.92 | KLKB1 (0.36) | GAAALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL31222122 | 0.92 | ALDH1A1 (0.36) | GAAALDH1A1MAPTCYP1A2CYP2C9 | |
| SCHEMBL31222098 | 0.92 | ALDH1A1 (0.39) | GAAALDH1A1MAPTCYP1A2CYP2C9 | |
| SCHEMBL31222099 | 0.91 | ALDH1A1 (0.40) | GAAALDH1A1MAPTCYP1A2CYP2C9 | |
| SCHEMBL31222094 | 0.86 | GAA (0.47) | GAAALDH1A1MAPTCYP1A2CYP2C9 | |
| SCHEMBL31222124 | 0.84 | GAA (0.40) | GAAALDH1A1MAPTCYP1A2CYP2C9 | |
| SCHEMBL31222076 | 0.83 | GAA (0.42) | GAAALDH1A1MAPTCYP1A2CYP2C9 | |
| SCHEMBL31222106 | 0.82 | GAA (0.39) | GAAALDH1A1MAPTCYP1A2CYP2C9 | |
| SCHEMBL31222132 | 0.82 | PTGS2 (0.36) | GAAALDH1A1MAPTHPGDMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118994136-A | Pyrazole compound containing N1-heterocycle, and preparation method and application thereof | 安阳师范学院 | 2024-11-22 | — | — | CN | disclosed |