Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 3/20 | 0.38 |
| ▸ | RAB9A | P51151 | 3/20 | 0.38 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.37 |
| ▸ | GAA | P10253 | 3/20 | 0.37 |
| ▸ | PIM1 | P11309 | 2/20 | 0.36 |
| ▸ | CSNK2B | P67870 | 2/20 | 0.36 |
| ▸ | CSNK2A1 | P68400 | 2/20 | 0.36 |
| ▸ | PIM2 | Q9P1W9 | 2/20 | 0.36 |
| ▸ | FLT3 | P36888 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 4/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.34 |
| ▸ | PDE7A | Q13946 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31222071 | 0.89 | GAA (0.43) | NPC1RAB9AKMT2AGAAMEN1 | |
| SCHEMBL31222129 | 0.87 | GRM4 (0.39) | NPC1RAB9AGRM4KMT2AGAA | |
| SCHEMBL31222121 | 0.86 | HSD17B10 (0.39) | RAB9AKMT2AGAAPIM1MEN1 | |
| SCHEMBL31222101 | 0.84 | GRM4 (0.37) | NPC1RAB9AGRM4KMT2AGAA | |
| SCHEMBL31222103 | 0.84 | ALDH1A1 (0.43) | NPC1KMT2AGAAMEN1ALDH1A1 | |
| SCHEMBL31222087 | 0.82 | GRM4 (0.37) | NPC1RAB9AGRM4KMT2AGAA | |
| SCHEMBL31222108 | 0.82 | DGAT1 (0.41) | GRM4KMT2AGAAMEN1ALDH1A1 | |
| SCHEMBL31222084 | 0.82 | HSD17B10 (0.38) | GRM4KMT2AGAAPIM1CSNK2B | |
| SCHEMBL31222119 | 0.81 | GAA (0.39) | NPC1RAB9AGRM4KMT2AGAA | |
| SCHEMBL31222102 | 0.80 | MEN1 (0.45) | KMT2APIM1MEN1ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118994136-A | Pyrazole compound containing N1-heterocycle, and preparation method and application thereof | 安阳师范学院 | 2024-11-22 | — | — | CN | disclosed |