Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 4/20 | 0.36 |
| ▸ | GFER | P55789 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | RXFP1 | Q9HBX9 | 3/20 | 0.35 |
| ▸ | PPARG | P37231 | 1/20 | 0.35 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.35 |
| ▸ | AURKA | O14965 | 4/20 | 0.35 |
| ▸ | ADORA2A | P29274 | 3/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31222119 | 0.91 | GAA (0.39) | SMN1; SMN2GAAALDH1A1MAPTKMT2A | |
| SCHEMBL31222076 | 0.90 | GAA (0.42) | SMN1; SMN2GAAALDH1A1KDM4EHPGD | |
| SCHEMBL31222103 | 0.90 | ALDH1A1 (0.43) | SMN1; SMN2GAAALDH1A1MAPTTDP1 | |
| SCHEMBL31222121 | 0.90 | HSD17B10 (0.39) | SMN1; SMN2GAAALDH1A1KDM4EHPGD | |
| SCHEMBL31222088 | 0.86 | AURKA (0.38) | SMN1; SMN2GAAALDH1A1KDM4EHPGD | |
| SCHEMBL31222112 | 0.84 | ALDH1A1 (0.37) | SMN1; SMN2GAAALDH1A1KDM4EHPGD | |
| SCHEMBL31222122 | 0.82 | ALDH1A1 (0.36) | SMN1; SMN2GAAALDH1A1KDM4EHPGD | |
| SCHEMBL31222090 | 0.82 | LMNA (0.38) | SMN1; SMN2GAAALDH1A1KDM4EHPGD | |
| SCHEMBL31222123 | 0.81 | ALDH1A1 (0.35) | SMN1; SMN2GAAALDH1A1KDM4EHPGD | |
| SCHEMBL31222102 | 0.80 | MEN1 (0.45) | ALDH1A1KDM4EHPGDMAPTTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118994136-A | Pyrazole compound containing N1-heterocycle, and preparation method and application thereof | 安阳师范学院 | 2024-11-22 | — | — | CN | disclosed |