Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 5/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | P2RX7 | Q99572 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 3/20 | 0.35 |
| ▸ | RAB9A | P51151 | 3/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.35 |
| ▸ | AVPR2 | P30518 | 1/20 | 0.35 |
| ▸ | GPR27 | Q9NS67 | 1/20 | 0.35 |
| ▸ | KCNMA1 | Q12791 | 1/20 | 0.34 |
| ▸ | GCK | P35557 | 1/20 | 0.34 |
| ▸ | CNR2 | P34972 | 2/20 | 0.34 |
| ▸ | CNR1 | P21554 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31222084 | 0.89 | HSD17B10 (0.38) | GAAALDH1A1MAPTLMNAP2RX7 | |
| SCHEMBL31222116 | 0.87 | GAA (0.42) | GAAALDH1A1MAPTTDP1LMNA | |
| SCHEMBL31222077 | 0.85 | GAA (0.45) | GAAALDH1A1MAPTTDP1LMNA | |
| SCHEMBL31222071 | 0.82 | GAA (0.43) | GAAALDH1A1MAPTTDP1LMNA | |
| SCHEMBL31222091 | 0.82 | GAA (0.43) | GAAALDH1A1MAPTTDP1LMNA | |
| SCHEMBL31222078 | 0.82 | GAA (0.43) | GAAALDH1A1MAPTTDP1LMNA | |
| SCHEMBL31222074 | 0.82 | GAA (0.43) | GAAALDH1A1MAPTTDP1LMNA | |
| SCHEMBL31222097 | 0.81 | HSD17B10 (0.45) | GAAALDH1A1MAPTTDP1LMNA | |
| SCHEMBL31222123 | 0.79 | ALDH1A1 (0.35) | GAAALDH1A1MAPTTDP1KMT2A | |
| SCHEMBL31222118 | 0.79 | LMNA (0.38) | GAAALDH1A1MAPTLMNAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118994136-A | Pyrazole compound containing N1-heterocycle, and preparation method and application thereof | 安阳师范学院 | 2024-11-22 | — | — | CN | disclosed |